RESPIRATORY FAILURE

This study tests a computer program that gives real-time feedback to doctors to help them set breathing machines more safely for critically ill patients with lung injury or respiratory failure. About 208 adults on breathing machines will be randomly assigned to either standard ca…

This study tests a new breathing device called Biphasic Cuirass Ventilation (BCV) against standard non-invasive ventilation in 50 adults who are at high risk of breathing failure after being taken off a mechanical ventilator. Participants will be randomly assigned to receive eith…

This study tests whether an improved non-invasive ventilation (NIV) mask can lower how often people need to breathe compared to a standard mask. About 60 adults who already use NIV for respiratory problems will try both masks for one hour each. Researchers will measure breathing …

This study tests two ways to train the breathing muscles of patients on ventilators to help them wean off the machine. About 60 adults with respiratory failure will be randomly assigned to one of two training methods. The goal is to see which method leads to faster and more succe…

This study tests a procedure called cryoablation, which uses cold to temporarily freeze nerves around broken ribs. The goal is to reduce severe pain, improve breathing, and prevent complications like pneumonia. About 30 adults with multiple rib fractures will be randomly assigned…

This study looks at how different levels of pressure from a breathing machine (ventilator) affect the lungs and diaphragm in 25 ICU patients with respiratory failure. Each patient will try three pressure settings to see which one helps them breathe more efficiently and with less …

This study looks at whether a chest CT scan gives extra information beyond a chest X-ray for ICU patients with respiratory failure. Researchers will review records of 50 patients to see if CT findings changed treatment plans. The goal is to reduce unnecessary scans and risks for …

This study will observe 1,200 adults admitted to resuscitation rooms in French hospitals. Researchers want to see if patients who go straight to the resuscitation room do better than those who are treated in the emergency department first. The goal is to understand how care is de…

This study looks at whether heart rate variability—natural changes in time between heartbeats—can signal when a patient on high-flow oxygen needs a flow adjustment. Researchers will slowly lower the oxygen flow in 20 adults already on this therapy and watch for changes in heart r…

This study tests whether a bedside lung ultrasound can help doctors see how well collapsed lung areas reopen in obese patients on breathing machines. About 45 adults with a BMI of 33 or higher will be scanned before, during, and after a standard lung-opening procedure. The goal i…