RESPIRATORY FAILURE

This study tested two ways of using a breathing machine during heart bypass surgery to see which one leads to fewer lung problems. Over 1,500 adults having planned heart surgery took part. One group had the breathing machine turned off during bypass, while the other received very…

This study looked at whether giving inhaled heparin to COVID-19 patients on ventilators could help them get off the breathing machine sooner and lower the risk of death. Researchers combined data from several smaller trials in Australia, Ireland, the US, and the UK. A total of 57…

This study tested whether adding L-arginine and liposomal vitamin C supplements to standard pulmonary rehabilitation could reduce fatigue in people with COPD and chronic respiratory failure. The trial involved 101 participants aged 40 to 90 from 12 Italian hospitals. The main goa…

This study tested whether adding a second nerve block (rectus sheath block) to a standard chest wall block (pectointercostal fascial plane block) could better control pain after heart surgery. 62 adults undergoing elective heart surgery were randomly assigned to receive either th…

This study tested whether critically ill patients on breathing machines could safely control their own anxiety medication (dexmedetomidine) instead of having a nurse give it. 161 adults in the ICU were randomly assigned to either self-manage their sedation or receive standard nur…

This study tested whether a computer-driven system (Smartcare/PS) could shorten the time children spend on a breathing machine compared to standard care. Thirty children with respiratory failure took part. The goal was to see if the computer could help them start breathing on the…

This study looked at 48 ICU patients on breathing machines to understand how doctors can better reopen collapsed parts of the lung. Researchers measured lung function before and after a procedure that briefly increases pressure to open the lungs. The goal was to find which signs …

This study looked at 77 adults in the intensive care unit who needed a tracheostomy (a breathing tube through the neck) while on a ventilator. Doctors used either a camera (bronchoscopy) or ultrasound to guide the procedure. The goal was to see how each method affected breathing …

This study looked at 60 critically ill adults in the ICU who needed a breathing tube. Researchers compared complication rates before and after a checklist was introduced. The goal was to see if the checklist helped prevent dangerous drops in oxygen or blood pressure during the pr…

This study looked at whether certain blood test ratios can predict the risk of death in critically ill adults in the ICU. Researchers analyzed medical records from 212 patients to see if these ratios are linked to survival. The goal is to help doctors quickly identify high-risk p…

This study looked at 250 COVID-19 patients with severe breathing problems who were treated with a CPAP machine (a mask that pushes air into the lungs). Researchers collected information on how many patients survived, how many needed a breathing tube, and what happened over 6 mont…

This study tested three common ways to set a breathing machine (ventilator) for critically ill adults with respiratory failure. The goal was to see if the choice of mode affects how many days patients are alive and off the ventilator. 566 patients took part across multiple ICUs. …

This study looked at 24 critically ill patients on breathing machines to see if a simple method (Pressure Muscle Index) can accurately measure how hard they are breathing. Researchers compared it to the standard, more invasive technique. The goal was to find the best ventilator s…

This study looked at whether measuring brain activity during a breathing test can help predict if a patient on a ventilator will successfully breathe on their own. Researchers monitored 70 ICU patients as they attempted a spontaneous breathing trial, focusing on tiny brain signal…

This study looked at 600 COVID-19 patients with severe breathing problems who were treated with high-flow nasal oxygen and placed on their stomachs while awake. The goal was to see if this combination could reduce the need for breathing tubes and lower death rates. Researchers al…

This small pilot study tested whether it is possible to set personalized blood pressure targets for critically ill patients based on their brain's oxygen levels. Researchers monitored 16 ICU patients with respiratory failure or shock for 24 hours to find each patient's optimal bl…

This study looked at 28 ICU patients on breathing machines to see if a diaphragm ultrasound could detect a specific breathing problem called double triggering. Researchers compared ultrasound results to standard ventilator readings. The goal is to find better ways to monitor and …