Oxford researchers seek better way to open collapsed lungs in ICU
NCT ID NCT05508724
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This University of Oxford study looked at 48 ICU patients on ventilators for respiratory failure. Doctors sometimes inflate the lungs briefly (a recruitment manoeuvre) to reopen collapsed areas, but it's unclear when this helps. Researchers used a device to measure lung volume and see if pressure-volume curves can predict which patients benefit. The goal is to improve decision-making for this common ICU procedure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better decide when to perform recruitment manoeuvres in ventilated patients, potentially improving lung function.
- What could go wrong
- This is a small, observational study (48 participants) that aims to understand a measurement technique, not to test a new treatment. Results may not apply to all ICU patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for RESPIRATORY DISTRESS SYNDROME are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Royal Berkshire Hospital, Royal Berkshire Foundation Trust
Reading, RG1 5AN, United Kingdom
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Spinal zaps could reboot breathing after brain injury
- Can gentle oscillations help premature babies breathe better?
- Could a tiny tube spare preterm babies from breathing machines?
- Could a spirometer test guide breathing support in respiratory failure?
- Can an Oxygen-Boosting drug help when all else fails?
- Can a Diaphragm-Sensing ventilator mode reduce breathing asynchrony?