Simple supplements may fight fatigue in advanced lung disease
NCT ID NCT06439875
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested whether taking L-arginine and liposomal vitamin C supplements twice daily could reduce fatigue in people with COPD and chronic respiratory failure. 101 patients were randomly assigned to receive the supplements or a placebo during a 28-day pulmonary rehabilitation program. The main goal was to measure changes in fatigue severity using a standard questionnaire.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
L-arginine and liposomal vitamin C
What this could lead to
If it works, this could offer a simple supplement to ease fatigue and improve daily life for people with advanced COPD.
What could go wrong
This is a small, completed trial with no phase designation, so results may not be conclusive or widely applicable. Supplements may not work for everyone.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Istituti Clinici Scientifici Maugeri IRCCS
Lumezzane, Brescia, 25065, Italy
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Istituti Clinici Scientifici Maugeri IRCCS
Bari, 70124, Italy
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Istituti Clinici Scientifici Maugeri Irccs
Telese Terme, Benevento, 82037, Italy