Can early oxygen therapy prevent breathing failure after chest trauma?

NCT ID NCT03943914

Completed Prevention Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether giving breathing support early (non-invasive ventilation and high-flow nasal oxygen) to people with chest injuries and low oxygen levels could prevent them from needing a breathing tube. 144 patients in the ICU took part. The goal was to see if this early approach works better than waiting until breathing gets worse.

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Conditions

The condition(s) this trial relates to.

Thoracic Injuries respiratory failure prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHEST INJURIES RESPIRATORY FAILURE

Contacts and locations

Locations

AP-HM - Hôpital de la Timone

Marseille, 13385, France
APHP - Hôpital Beaujon

Clichy, 92110, France
CH d'Annecy

Annecy, France
CH de Pau

Pau, 64000, France
CHU Amiens-Picardie

Amiens, 80054, France
CHU de Bordeaux

Bordeaux, 33076, France
CHU de Clermont-Ferrand

Clermont-Ferrand, 63003, France
CHU de Nîmes

Nîmes, 30029, France
CHU de Poitiers

Poitiers, 86021, France
CHU de Saint Etienne

Saint-Priest-en-Jarez, 42270, France
CHU de Strasbourg - Hôpital Civil

Strasbourg, 67091, France
CHU de Strasbourg -Hôpital de Hautepierre

Strasbourg, 67200, France
HCL - Hôpital Lyon Sud

Pierre-Bénite, 69495, France
Hôpital Robert Picqué

Villenave-d'Ornon, 33882, France

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