New breathing vest could reduce need for Re-Intubation in ICU patients

NCT ID NCT07067502

Not yet recruiting Disease control Sponsor: University of Missouri-Columbia Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 2 times

Summary

This study compares a new type of breathing device (biphasic cuirass ventilator) to standard non-invasive ventilation in 50 high-risk patients who are about to have their breathing tube removed. The goal is to see if the new device can reduce the number of patients who need to be put back on a breathing tube. Participants are adults in the ICU who doctors think are at high risk for breathing failure after extubation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Biphasic cuirass ventilator (negative pressure ventilation device)
What this could lead to: If it works, this could offer a better way to help high-risk patients breathe after a breathing tube is removed, possibly reducing the need for re-intubation.
What could go wrong: This is a small, early-stage study with only 50 participants, so results may not apply to everyone. The device may not work as well as standard care, and some patients cannot use it due to chest conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EXTUBATION FAILURE RESPIRATORY FAILURE

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