POSTOPERATIVE DELIRIUM

This study tested a new approach during brain surgery: gently stimulating the diaphragm (the main breathing muscle) to see if it could reduce common post-surgery problems like confusion (delirium) and lung infections. The trial involved 120 adults having brain tumor surgery. The …

This study looked at whether being in a room with natural light after heart surgery can help prevent delirium—a sudden confusion that often happens in the first day after surgery. Researchers compared 448 adults who had heart surgery and stayed in an ICU with either natural or ar…

This study looked at 65 older adults getting a less-invasive heart valve replacement (TAVR). Researchers compared two sedation drugs, propofol and dexmedetomidine, to see which one better protects kidney function, reduces confusion after surgery, and lowers the risk of side effec…

This study looked at whether giving a small amount of s-ketamine during chest surgery can help prevent delirium (sudden confusion) in patients aged 60 and older. The trial involved 520 people having non-cardiac chest surgery. Researchers compared s-ketamine to another drug, dexme…

This study tested a special anesthesia method during heart surgery to see if it could reduce confusion, pain, and the need for blood pressure medicines in older adults. 70 people aged 60 and older took part. The approach used brain monitoring to guide anesthesia and a planned pai…

This study looked at 50 adults having heart bypass surgery to see if one sedative (dexmedetomidine) causes less confusion after surgery than another (midazolam). The goal was to find a way to reduce postoperative delirium, a common problem after heart surgery. Researchers checked…

This study tested two different nerve block techniques to control pain after open-heart surgery. 42 adults were randomly assigned to receive either one block or a combination of two blocks. The goal was to see which approach provided better pain relief and helped patients recover…

This study tested two different methods of pain control during back surgery to see which one works better. 29 adults having 1-2 level lower back fusion surgery were randomly assigned to receive either a nerve block before surgery or a large dose of numbing medicine at the end. Th…

This study tested whether using an EEG (brain-wave) monitor during general anesthesia could reduce confusion and pain after dental surgery in children. 92 kids aged 4-10 were split into two groups: one got standard anesthesia care, the other got extra EEG guidance. The goal was t…

This study tested whether the sleep medication suvorexant can help older adults (60+) sleep better and reduce confusion (delirium) after heart surgery in the intensive care unit. One hundred participants received either suvorexant or a placebo for seven nights. The goal was to se…

This study looked at how often patients develop confusion after surgery (postoperative delirium) and what factors increase the risk. Researchers tracked over 2,400 adults in Spanish hospitals who had surgery requiring an overnight stay. The goal is to use this information to crea…

This study followed 610 adults who had heart surgery to see how often they develop postoperative delirium—a sudden state of confusion that can come and go. Researchers collected information on known risk factors like age, high blood pressure, and diabetes, and tracked outcomes su…

This study tested whether a gentle electrical stimulation at specific acupoints (Neiguan and Shenmen) could reduce confusion (delirium) in 226 older adults after abdominal surgery. Researchers also measured brain wave changes to understand how it might work. The goal is to find a…

This study looked at whether two substances in the blood, zonulin and interleukin-8, are linked to confusion (delirium) after hip fracture surgery. Researchers measured these markers before and after surgery in 73 older adults. The goal was to see if these markers could help pred…