PERIPHERAL ARTERY DISEASE

This study tested whether gentle electrical stimulation of the ear (targeting a nerve connected to the heart and blood vessels) could improve blood vessel function in people with peripheral artery disease (PAD). Eleven participants with PAD tried both the real stimulation and a f…

This early study tested the safety and performance of a special balloon coated with the drug sirolimus. The balloon is used to open narrowed arteries in the leg (femoropopliteal arteries) in patients with peripheral artery disease. The goal was to see if the drug-coated balloon c…

This study tested a medical device called an orbital atherectomy system to treat severe, hardened blockages in the leg arteries of Japanese patients with peripheral artery disease (PAD). The goal was to see if the device could safely open these difficult blockages to improve bloo…

This study looked back at 50 patients who had a procedure to clear severely hardened blockages in their leg arteries. The goal was to see how well the treatment worked over three years, specifically checking if patients needed another procedure on the same artery. Researchers col…

This large study tested whether sending exercise guides and motivational tips through the mail could help older women become more active and improve their health. It enrolled nearly 50,000 women aged 60+ to see if this remote program could reduce serious health problems like hear…

This study tested if using video calls with specialists could get faster care for people in rural areas with serious foot sores from diabetes and poor blood flow. Researchers compared patients who had video consultations to those who had to travel for standard in-person visits. T…

This study aimed to find the best simple bedside test for detecting poor leg circulation (peripheral arterial disease) in people with diabetes. Researchers compared several quick tests, like blood pressure measurements in the ankle and toe, against more complex imaging scans. The…

This study tested whether specially designed shoes could help people with peripheral artery disease (PAD) walk more easily. PAD causes leg pain when walking due to poor blood flow. Ten participants tried shoes with carbon fiber or spring-loaded soles for three months to see if th…

This study tested whether changing how an invitation email is worded affects how many people sign up for a clinical trial. Researchers invited over 5,000 patients with peripheral artery disease to join a trial about a home walking program. They compared two email styles: one wher…

This study aimed to understand how a special drug-coated balloon releases its medication into the bloodstream when used to treat narrowed leg arteries. It involved a small group of patients with leg pain from poor circulation. Researchers took blood samples at different times aft…