Sound wave device clears calcified leg arteries in new study

NCT ID NCT05007925

First seen May 06, 2026 · Last updated May 06, 2026

Summary

This study tested a device that uses sound waves to break up calcium buildup in the arteries below the knee in people with peripheral artery disease (PAD). 250 participants were treated, and the main goal was to see if the device could safely open blocked arteries without serious complications. The approach aims to improve blood flow and reduce the need for more invasive procedures.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Ascension St Johns Heart & Vascular Center

    Bartlesville, Oklahoma, 74006, United States

  • Barnes-Jewish Hospital

    St Louis, Missouri, 63110, United States

  • Baylor Scott & White - The Heart Hospital Baylor

    Plano, Texas, 75093, United States

  • Bryn Mawr Hospital

    Bryn Mawr, Pennsylvania, 19010, United States

  • Cardiothoracic and Vascular Surgeons

    Austin, Texas, 78756, United States

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Charlotte Radiology

    Charlotte, North Carolina, 28202, United States

  • Columbia University Irving Medical Center/NYPH

    New York, New York, 10032, United States

  • Karolinen-Hospital Hüsten

    Arnsberg, 59759, Germany

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • McLaren Bay Heart and Vascular

    Bay City, Michigan, 48708, United States

  • McLaren Greater Lansing

    Lansing, Michigan, 48910, United States

  • MedStar Washington Hospital Center

    Washington D.C., District of Columbia, 20010, United States

  • Medical University of South Carolina (MUSC)

    Charleston, South Carolina, 29425, United States

  • Medstar Montgomery Medical Center

    Olney, Maryland, 20832, United States

  • Midwest Cardiovascular Research Foundation

    Davenport, Iowa, 52803, United States

  • Mt. Sinai Hospital

    New York, New York, 10029, United States

  • NYU Langone Health

    New York, New York, 10016, United States

  • NYU Langone Medical Center

    New York, New York, 10016, United States

  • North Carolina Heart & Vascular

    Raleigh, North Carolina, 27607, United States

  • North Mississippi Medical Center

    Tupelo, Mississippi, 38801, United States

  • Ohio Health Research Institute

    Columbus, Ohio, 43214, United States

  • Piedmont Heart Institute

    Atlanta, Georgia, 30309, United States

  • Pinnacle Health Cardiovascular Institute

    Harrisburg, Pennsylvania, 17101, United States

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • Scripps Memorial Hospital

    La Jolla, California, 92037, United States

  • Sentara Norfolk General Hospital

    Norfolk, Virginia, 23507, United States

  • Southcoast Hospitals Group

    New Bedford, Massachusetts, 02740, United States

  • St. Helena Hospital

    St. Helena, California, 94574, United States

  • St. Luke's Hospital

    Kansas City, Missouri, 64111, United States

  • Stanford Hospital

    Palo Alto, California, 94304, United States

  • Tallahassee Memorial Hospital

    Tallahassee, Florida, 32308, United States

  • Texas Health Presbyterian Hospital

    Dallas, Texas, 75231, United States

  • The Christ Hospital

    Cincinnati, Ohio, 45219, United States

  • The Miriam Hospital

    Providence, Rhode Island, 02906, United States

  • UC Davis Health

    Sacramento, California, 95817, United States

  • UCSF Fresno

    Fresno, California, 93720, United States

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • Universitäts-Herzzentrum Freiburg & Bad Krozingen

    Bad Krozingen, 79189, Germany

  • Universitätsklinikum Leipzig AoR

    Leipzig, 04103, Germany

  • Universitätsklinikum der Ruhr-Universitaet Bochum

    Bad Oeynhausen, 32545, Germany

  • VA Puget Sound Health Care Systems - Seattle

    Seattle, Washington, 98108, United States

  • Wellmont Cardiology Services dba CVA Heart Institute

    Kingsport, Tennessee, 37660, United States

Conditions

Explore the condition pages connected to this study.