Simple antibacterial wash could slash deadly graft infections in vascular surgery

NCT ID NCT07678632

Not yet recruiting Prevention Sponsor: Hamilton Health Sciences Corporation Source: ClinicalTrials.gov ↗

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This study tests whether washing the surgical wound and the new prosthetic graft with a hypochlorous acid solution at the end of surgery can prevent infections. Participants are adults having open surgery to insert a synthetic bypass graft for narrowed or blocked arteries. The study will track infections for 12 months and also assess whether a larger trial is feasible.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: hypochlorous acid
What this could lead to: If effective, this simple wash could become a standard step in vascular surgery, preventing life-threatening graft infections and reducing amputations and deaths.
What could go wrong: This is a small pilot study, so results may not be conclusive. The solution might not reduce infection rates enough to justify a larger trial, and individual patient factors could affect outcomes.

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Conditions

The condition(s) this trial relates to.

peripheral arterial disease prosthesis-related infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

VASCULAR PROSTHETIC GRAFT INFECTION

Contacts and locations

Locations

Hamilton Health Sciences

Hamilton, Ontario, L8L 2X2, Canada

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