Hamilton Health Sciences Corporation

This study tests whether a catheter-based procedure to close a small pouch in the heart (the left atrial appendage) can prevent strokes or blood clots in people with atrial fibrillation who are already taking blood thinners. About 4,000 participants with a high risk of stroke wil…

This study tests an experimental drug called tideglusib in people with a genetic heart condition that causes dangerous heart rhythms. The goal is to see if the drug can reduce the number of extra heartbeats and prevent serious rhythm events. About 120 adults with a confirmed gene…

This study tests whether giving two medicines, tranexamic acid and desmopressin, before surgery can reduce bleeding in patients with kidney problems. About 100 adults with chronic kidney disease or acute kidney injury who need noncardiac surgery will take part. The goal is to see…

This study looks at whether using a dye called indocyanine green (ICG) alone is as accurate as the usual two-method approach (ICG plus a radioactive tracer) for finding cancer that has spread to lymph nodes in early vulvar cancer. About 58 women with early-stage vulvar cancer wil…

This study tests whether a numbing injection (bupivacaine) into a nerve cluster behind the nose can reduce pain after minimally invasive pituitary tumor surgery. About 108 adults will receive either the nerve block, a placebo, or no extra injection, and report their pain levels o…

This study compares two common methods for anterior cervical spine surgery: the Smith-Robinson approach and the strap-splitting approach. Both use the same skin cut but differ in how the surgeon reaches the spine. The goal is to see which approach leads to fewer swallowing and vo…