Massive trial aims to slash infection risk in hip and knee replacements

NCT ID NCT06126614

Recruiting now Prevention Sponsor: Hamilton Health Sciences Corporation Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests if using antiseptic washes and placing antibiotics directly into the wound during hip or knee replacement surgery can lower the chance of a serious infection that requires another operation. Over 21,000 adults getting a joint replacement will be randomly assigned to one of six treatment combinations. Researchers will track infections for one year after surgery to find the best way to prevent this common complication.

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Conditions

The condition(s) this trial relates to.

periprosthetic joint infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIPROSTHETIC JOINT INFECTION

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Hamilton Health Sciences - Juravinski Hospital and Cancer Centre
RECRUITING

Hamilton, Ontario, L8V 1C3, Canada