Which surgery works best for infected hip or knee replacements?

NCT ID NCT02734134

First seen May 30, 2026 · Last updated Jun 09, 2026 · Updated 4 times

Summary

This study looked at 343 adults with infections in their artificial hip or knee joints. It compared two common surgeries: one-stage (removing and replacing the joint in one operation) and two-stage (removing the joint, treating the infection, then replacing it later). The main goal was to see which approach better prevents the infection from coming back within a year.

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Contacts and locations

Locations

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Hospital for Special Surgery

    New York, New York, 10021, United States

  • Midwest Orthopaedics at Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • OrthoCarolina Research Institue

    Charlotte, North Carolina, 28207, United States

  • Rothman Institute at Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

Conditions

Explore the condition pages connected to this study.

Conditions inferred from the trial description

These were inferred from the trial's summary, not listed by the trial registrant.