Could a simple injection cut pain after brain surgery?
NCT ID NCT06353529
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether injecting a numbing medication (bupivacaine) near a nerve cluster in the nose can reduce pain after minimally invasive pituitary tumor removal. About 108 adults will be randomly assigned to receive the nerve block, a placebo (saline), or no extra injection. Researchers will measure pain levels and painkiller use over the first 24 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- bupivacaine with epinephrine
- What this could lead to
- If it works, this could provide a simple way to reduce pain and the need for painkillers after pituitary surgery.
- What could go wrong
- This is a small, early-phase trial focused on short-term pain relief. The nerve block may not significantly improve outcomes over placebo or sham, and individual results may vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hamilton General Hospital
RECRUITINGHamilton, Ontario, L8L 2X2, Canada
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