Could a diabetes drug tame a rare heart rhythm disorder?
NCT ID NCT06174220
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a drug called tideglusib in 120 people with a genetic heart condition that can cause dangerous heart rhythms. The drug aims to reduce abnormal heartbeats and improve heart function. Participants will take either tideglusib or a placebo daily for about a year to see if it helps control the condition.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Tideglusib
- What this could lead to
- If successful, this could point toward a new treatment to control heart rhythm problems and slow disease progression in arrhythmogenic cardiomyopathy.
- What could go wrong
- This is a mid-stage trial with only 120 participants, so results may not apply to everyone. The drug may not reduce abnormal heartbeats or could cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ARRHYTHMOGENIC CARDIOMYOPATHY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Email: •••••@•••••
Locations
-
Hamilton General Hospital
RECRUITINGHamilton, Ontario, L8L 2X2, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
-
Heart Health Institute Research Inc
RECRUITINGScarborough Village, Ontario, M1E 4B9, Canada
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Hopital du Sacré-Coeur de Montréal
NOT_YET_RECRUITINGMontreal, Quebec, H4J 1C5, Canada
Contact
Contact
Contact
-
Kingston General Hospital
NOT_YET_RECRUITINGKingston, Ontario, K7L 2V7, Canada
Contact
Contact
-
London Health Sciences Centre
RECRUITINGLondon, Ontario, N6A 5A5, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
McGill University Health Centre
NOT_YET_RECRUITINGMontreal, Quebec, H4A 3J1, Canada
Contact
Contact
-
Montreal Heart Institute
RECRUITINGMontreal, Quebec, H1T 1C8, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
Contact
-
NL Health Services
RECRUITINGSt. John's, Newfoundland and Labrador, A1B 3V6, Canada
Contact
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Newmarket Electrophysiologist Research Group 'NERG'
NOT_YET_RECRUITINGNewmarket, Ontario, L3Y 2P9, Canada
Contact
Contact
-
Nova Scotia Health
RECRUITINGHalifax, Nova Scotia, B3H 2Y9, Canada
Contact
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
St. Michael's Hospital
NOT_YET_RECRUITINGToronto, Ontario, M5B 1W8, Canada
Contact
Contact
-
Sunnybrook Health Sciences Centre
NOT_YET_RECRUITINGToronto, Ontario, M4N 3M5, Canada
Contact
Contact
-
University Institute of Cardiology and Pneumology of Quebec
RECRUITINGQuébec, Quebec, G1V 4G5, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
University of British Columbia
RECRUITINGVancouver, British Columbia, V6Z 1Y6, Canada
Contact
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
University of Calgary
RECRUITINGCalgary, Alberta, T2N 2T9, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
-
University of Ottawa Heart Institute
NOT_YET_RECRUITINGOttawa, Ontario, K1Y 4W7, Canada
Contact
Contact
Contact
-
Victoria Cardiac Arrhythmia Trials Inc.
RECRUITINGVictoria, British Columbia, V8Z 0B9, Canada
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Global registry aims to unlock clues for heart transplant success in adults born with heart defects
- Gene hunt launched for kids with heart muscle disease
- Heart inflammation clues sought in rare heart disease
- Heart condition costs under the microscope in massive hospital study
- Heart disease detective: 1,000-Person study hunts for hidden genetic triggers of sudden cardiac death
- New PET scan could spot hidden heart damage in rare condition