Can a simple drug stop dangerous bleeding in kidney patients during surgery?

NCT ID NCT06337838

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether giving two common drugs, tranexamic acid and desmopressin, before surgery can reduce bleeding in patients with chronic kidney disease or acute kidney injury. About 100 adults having noncardiac surgery will be randomly assigned to receive one or both drugs or a placebo. The goal is to see if these drugs are safe and effective at preventing serious bleeding complications.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Hospitalier de L'Universite de Montreal (CHUM)

    ACTIVE_NOT_RECRUITING

    Montreal, Quebec, H2X 0A9, Canada

  • London Health Sciences Centre

    RECRUITING

    London, Ontario, N6A 5A5, Canada

  • McGill University University Health Centre

    RECRUITING

    Montreal, Quebec, H3H 2R9, Canada

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