PERIPHERAL ARTERIAL DISEASE

This study aims to find a safe and effective dose of a new drug called Etrinabdione for people with peripheral arterial disease (PAD), which causes poor blood flow and pain in the legs. It will involve 30 adults with moderate to severe PAD who will take the drug twice daily for a…

This study is testing a new drug-coated balloon device to treat blocked leg arteries in people with peripheral artery disease. Researchers want to see if this new device, coated with a drug called everolimus, works as well and is as safe as currently available paclitaxel-coated b…

This study is testing a new injectable drug called SRSD107 for people with chronic coronary artery disease (CAD) or peripheral artery disease (PAD). The main goals are to see how the drug behaves in the body, if it's safe, and how it affects certain blood markers. About 104 parti…

This study is testing a special balloon coated with medicine to treat blockages in the leg arteries. The device is already approved in Europe, and this trial aims to gather more information on how well it works, especially for longer blockages. Researchers will follow 200 partici…

This study is testing whether a special camera that measures oxygen levels in foot tissue can help doctors detect and monitor peripheral artery disease (PAD). Researchers will use the camera while participants perform simple leg lifts, comparing the results to standard medical te…

This study is testing if a special type of light exercise, where blood flow to the legs is partially restricted, can help people with peripheral artery disease (PAD) walk farther and feel better. Researchers will compare this new exercise method to standard rehab exercises in abo…

This study is testing whether using virtual reality (VR) headsets during leg artery surgery can help reduce patients' pain and anxiety. Patients having a minimally invasive procedure under local anesthesia will be randomly assigned to use VR or not. The main goal is to see if the…

This survey asks doctors to share their experiences using a new device called Liberant to remove fresh blood clots from arteries and veins in the arms and legs. The goal is to gather initial safety and performance data from at least 50 real-world cases. Doctors will report on how…

This study aims to understand how two common blood-thinning medications, aspirin and clopidogrel, affect inflammation in the arteries of people with silent atherosclerosis. Researchers will measure specific blood cell clusters linked to artery disease in 60 participants who have …

This early study aims to see if a special dye called LUMISIGHT can make inflammation inside blocked arteries visible to doctors. Researchers will test it on 25 people with severe carotid or leg artery disease who are already scheduled for surgery. They will compare images of arte…

This study aims to develop and test artificial intelligence (AI) tools that can predict which patients with abdominal aortic aneurysm or peripheral artery disease are at high risk for serious complications like heart attack, stroke, or death. Researchers will follow 1,100 patient…

This study aims to see if measurements from a CT scan patients already get can predict who will not improve with standard exercise therapy for leg artery disease. Researchers will analyze muscle quality and belly fat from these scans in 128 patients to see if they can identify no…