Common blood thinners may calm artery inflammation in at-risk patients
NCT ID NCT07169513
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether two widely used anti-platelet drugs, aspirin and clopidogrel, can reduce inflammatory markers in people with silent atherosclerosis (hardening of the arteries without symptoms). Researchers will measure changes in monocyte-platelet aggregates, a sign of inflammation, in 60 participants over time. The goal is to understand how these drugs affect the body's inflammatory response, not to treat symptoms directly.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Aspirin and clopidogrel (anti-platelet drugs)
- What this could lead to
- If successful, this could show that common anti-platelet drugs reduce inflammation in people with silent atherosclerosis, pointing toward better ways to prevent heart problems.
- What could go wrong
- This is a small, early mechanistic study (60 people) that measures blood markers, not clinical outcomes like heart attacks. It may not prove any direct benefit or change treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Guy's and St Thomas' NHS Foundation Trust
London, SE1 7EH, United Kingdom
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