Heart disease study: do aspirin and clopidogrel quiet the immune system?

NCT ID NCT07169513

First seen Nov 01, 2025 · Last updated Jun 06, 2026 · Updated 31 times

Summary

This study looks at whether two common anti-clotting drugs, aspirin and clopidogrel, can reduce inflammation in people with silent atherosclerosis (hardening of the arteries without symptoms). Researchers will measure how these drugs affect clusters of blood cells called monocyte-platelet aggregates, which are linked to worsening heart disease. The study involves 60 adults with hidden artery disease and aims to understand how these medications work on inflammation, not to treat or cure the condition.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Guy's and St Thomas' NHS Foundation Trust

    London, SE1 7EH, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

Conditions

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