New drug etrinabdione tested for leg artery disease

NCT ID NCT06774040

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This Phase IIa trial tests the safety and tolerability of a new drug called etrinabdione in 30 adults with peripheral arterial disease (PAD). Participants take the drug twice daily for 12 months, starting with a low dose and possibly moving to a higher dose if safe. Researchers will also check if the drug improves blood flow and walking ability.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

etrinabdione

What this could lead to

If successful, this could point toward a new treatment option for peripheral arterial disease that improves blood flow and walking ability.

What could go wrong

This is an early, small Phase IIa trial with only 30 participants. It primarily tests safety, not effectiveness, and the higher dose may be stopped if safety concerns arise.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Arterial Occlusive Diseases Chronic Limb-Threatening Ischemia intermittent vascular claudication peripheral arterial disease peripheral vascular disease vascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital Universitario Reina Sofía

    Córdoba, 14014, Spain