Laser tool aims to save legs from amputation

NCT ID NCT07472439

Not yet recruiting Disease control Sponsor: Angiodynamics, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This trial tests whether using a laser device (Auryon Atherectomy System) along with standard balloon angioplasty is safer and more effective than balloon angioplasty alone for treating severe blockages in the lower leg arteries. The study will enroll 50 people with critical limb ischemia, a serious condition that can lead to amputation. Researchers will compare outcomes like amputation rates, need for repeat procedures, and blood vessel openness over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Auryon Atherectomy System (laser device) used with balloon angioplasty
What this could lead to: If it works, this could offer a more effective way to clear leg blockages, potentially reducing the need for amputation or repeat procedures in people with critical limb ischemia.
What could go wrong: This is a small early-stage trial with only 50 participants, so results may not apply to everyone. The device also carries risks like vessel damage or incomplete clearing of blockages.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

limb ischemia peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIPHERAL ARTERIAL DISEASE

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Other studies related to the condition(s) this trial covers.