PANCREAS CANCER

This study tested a personalized vaccine made from each patient's unique cancer mutations (neoantigens) in people with pancreatic cancer. The vaccine was given after chemotherapy and before or after surgery to see if it is safe and boosts the immune system. 33 patients took part …

This study tested a sequence of drugs to control advanced pancreatic cancer that has spread. 75 patients received an initial combination of chemotherapy plus drugs that modify gene activity and boost the immune system. Those whose disease was controlled then received additional i…

This study tested two common antibiotics, cefoxitin and piperacillin-tazobactam, to see which one better prevents surgical site infections after a complex pancreatic surgery called pancreatoduodenectomy. Nearly 1,000 adults having this surgery took part. The goal was to find the …

This early-phase study tested whether adding the drug anakinra to standard chemotherapy is safe for people with advanced pancreatic cancer that has spread. Thirteen adults with metastatic pancreatic cancer took part. The main goal was to check for side effects, and researchers al…

This study tested a combination of two drugs, pembrolizumab (an immunotherapy) and azacitidine, in 36 people with advanced pancreatic cancer that had worsened after initial treatment. The goal was to see if this combination could slow or stop cancer growth. Participants received …

This early-phase study tested a new drug called SNB-101 in 21 people with advanced solid tumors (like colorectal, breast, or lung cancer) that had stopped responding to standard treatments. The drug is a nanoparticle version of SN-38, a chemotherapy agent, given by IV on days 1 a…

This study tested whether combining two oral chemotherapy drugs, vemurafenib and sorafenib, could help control advanced pancreatic cancer with a KRAS mutation. Ten patients whose cancer had worsened after at least two prior treatments took the drug combination. The main goal was …

This study tested a home monitoring system for people with advanced pancreatic cancer receiving a strong chemotherapy called FOLFIRINOX. The system tracked symptoms, weight, sleep, and activity to catch early signs of serious side effects. The goal was to see if remote monitoring…

This study tested a digital tool (a chatbot) to help cancer survivors learn about genetic testing for hereditary cancer risk. 50 adults who had certain cancers (like breast, ovarian, or prostate) took part. The goal was to see if the chatbot was easy to use and if it helped more …

This study looked at whether it is safe and possible to grow mini-tumors (organoids) from pancreatic cancer samples in the lab. Researchers took small tissue samples from 60 patients during surgery or a biopsy. They then tried to grow organoids and test different chemotherapy dru…