Double-Drug attack on tough pancreatic cancer shows promise in small trial

NCT ID NCT05068752

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a combination of two oral chemotherapy drugs, vemurafenib and sorafenib, in 10 people with advanced pancreatic cancer that has a specific genetic change called a KRAS mutation. All participants had already tried at least two standard treatments without success. The main goal was to see if the drug combination could control the cancer for at least 16 weeks. The approach targets a key signaling pathway in cancer cells.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm Neoplasm Metastasis pancreatic adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • HonorHealth Research Institute

    Scottsdale, Arizona, 85258, United States