New drug combo tested for tough pancreatic cancer

NCT ID NCT02021422

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase trial tested whether adding the drug anakinra to standard chemotherapy is safe for people with metastatic pancreatic cancer. Thirteen adults with advanced disease received the combination. The main goal was to check for side effects, not to see if it works.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
anakinra (Kineret) plus standard chemotherapy (oxaliplatin, irinotecan, fluorouracil)
What this could lead to
If this combination proves safe, it could point toward a new treatment option for metastatic pancreatic cancer.
What could go wrong
This is a very early, small Phase 1 safety trial with only 13 participants. It cannot prove the treatment works, and side effects or lack of benefit are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baylor Sammons Cancer Center

    Dallas, Texas, 75246, United States

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