PAIN MANAGEMENT

This study tests three ways to manage pain after lower abdominal surgery with a midline cut: spinal morphine, a nerve block, or standard painkillers. The goal is to see which method reduces the need for extra opioids and helps patients recover better. 66 adults will take part, an…

This study looks at whether cannabis oil can help reduce pain and improve sleep in people with fibromyalgia who have not found relief from other treatments. About 65 adults will take cannabis oil, and researchers will track pain levels, side effects, and how well patients follow …

This study tests whether a long-acting numbing medicine (liposomal bupivacaine) can reduce pain and the need for strong painkillers after nose surgery. About 72 adults having rhinoplasty or septorhinoplasty will receive either the long-acting drug or standard numbing medicine. Th…

This study looks at whether using a special device called Montage or Montage-CT to close the breastbone after heart surgery can lower the amount of strong painkillers (opioids) patients need. Researchers will review medical records of 150 adults who had planned heart surgery. The…

This study looks at whether a short pain education session before knee or hip replacement surgery can lower anxiety and pain after the operation. About 70 adults having elective joint replacement will either get the education (a booklet and video) or usual care. Researchers will …

This study looks at whether adding dexamethasone or dexmedetomidine to the usual numbing medicine (bupivacaine) can improve pain relief after shoulder arthroscopy. About 100 adults having elective shoulder surgery will be enrolled. The goal is to reduce pain and help recovery.

This study looks at whether a device called Buzzy Bee, which vibrates and cools the skin, can reduce pain in children during a dental numbing injection. About 30 healthy kids who need a tooth procedure will try the device. The goal is to make the shot less scary and painful, help…

This study looks at whether acupressure and back massage can help women who had a C-section feel less pain, less tired, and sleep better. About 111 new mothers will receive these gentle treatments after surgery. The goal is to find safe, drug-free ways to improve recovery without…

This study tests a program called COMPASS-NP for home care workers who have chronic pain. The program combines pain education, coping strategies, and safety tips to help workers feel better and stay active at work and in life. About 140 adults who work as home care workers and ha…

This study compares two types of acupuncture (personalized electro-acupuncture and auricular-acupuncture) with usual care for treating chronic pain. About 360 adults with musculoskeletal pain or fibromyalgia will be assigned to one of three groups. The goal is to see which approa…

This study looks at two different nerve blocks to control pain after breast removal surgery (modified radical mastectomy). About 70 women aged 18 to 65 will receive one of the two blocks. The goal is to see which block reduces the need for extra pain medicine and leads to fewer s…

This study tests whether a topical medication called ZYNRELEF, applied during shoulder replacement surgery, can control pain better than the standard nerve block with a catheter. About 86 adults having shoulder replacement will be randomly assigned to one of the two methods. Rese…

This study compares two procedures to relieve chronic tailbone pain (coccydynia) that hasn't improved with medication. 74 adults will receive either a heat-based radiofrequency treatment or an alcohol injection to block pain signals. The goal is to see which method provides bette…

This study compares two pain control methods after robotic prostate removal: one using opioids and one using only non-opioid medicines like ketamine, ketorolac, and acetaminophen. About 100 men aged 40-75 with prostate cancer will take part. The goal is to see if the opioid-free …

This study is testing a new wearable device that uses focused ultrasound to stimulate nerves in the arms and legs. Fifteen healthy adults will take part in nine sessions to see if the device is easy to use, comfortable, and works as intended. The goal is to gather information for…

This study looks at whether using a mild electrical current (neurostimulation) along with ultrasound makes nerve blocks work better for people having arm surgery. About 82 adults will take part. The goal is to see if the stimulation helps the block start faster and last longer, i…

This study aimed to see if a team of doctors, nurses, and pharmacists working together could help people recover better after anorectal surgery. It planned to enroll 126 adults and compare standard care to the team-based approach. However, the study was withdrawn before any parti…