New numbing shot could cut opioid use after nose jobs
NCT ID NCT05964868
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a long-acting numbing medication (liposomal bupivacaine) can better control pain after septorhinoplasty (nose surgery) compared to standard numbing drugs or a placebo. About 72 adults having nose surgery will receive one of three treatments at the end of their operation. Researchers will measure how much pain medication participants need and their reported pain levels. The goal is to see if this longer-lasting numbing agent can reduce opioid use and improve recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
liposomal bupivacaine (EXPAREL®)
What this could lead to
If it works, this could offer a longer-lasting pain relief option after nose surgery, potentially reducing the need for opioid painkillers.
What could go wrong
This is a single, small trial (72 people) testing a drug already used for other surgeries. The benefit may be small or not apply to all patients, and any new drug carries risks like allergic reactions.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PAIN MANAGEMENT are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Jessyka Lighthall
Hershey, Pennsylvania, 17033, United States