New painkiller aims to cut opioid use after shoulder surgery

This study tests whether a medication applied directly during shoulder replacement surgery (ZYNRELEF) can reduce the need for strong painkillers after the operation, compared to the standard method of using a nerve block with a catheter. About 86 adults having shoulder replacement will be randomly assigned to one of the two pain management approaches. Researchers will track how much opioid medication each group uses, their pain scores, and satisfaction with pain control.