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New study tests better pain control after abdominal surgery

NCT ID NCT07489872

Symptom relief Sponsor: Marmara University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares three ways to manage pain after lower abdominal surgery: a spinal injection of morphine, a nerve block in the abdominal wall, or standard painkillers. Sixty-six adults having surgery through a midline incision will be randomly assigned to one of these groups. The goal is to see which method reduces opioid use and improves recovery, with results expected to guide better pain management protocols.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
intrathecal morphine and rectus sheath block
What this could lead to
If successful, this could lead to better pain management protocols after abdominal surgery, reducing opioid use and improving patient comfort.
What could go wrong
This is a small, early-phase trial with only 66 participants, so results may not apply to all patients. The interventions also carry risks like nausea or rare complications from spinal injections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 66 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2025

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients over 18 years old * Patients undergoing lower abdominal surgery via midline incision. Exclusion Criteria: * Patients with solid organ dysfunction * Patients who receive opioid or corticosteroid medication prior to surgery * Patients with bleeding diathesis * Patients with psychiatric disorders * Patients who can not be contacted after surgery

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Conditions

The condition(s) this trial relates to.

agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pain management Postoperative analgesia

Contacts and locations

Locations

  • Marmara University School of Medicine

    Istanbul, Turkey (Türkiye)

  • Marmara University School of Medicine, Istanbul

    Istanbul, Turkey (Türkiye)

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