ORAL CANCER

This study is testing if using an ultrasound machine during surgery helps surgeons remove oral cancer more completely. About 200 patients will be randomly assigned to have standard surgery or surgery guided by real-time ultrasound images. The goal is to see if the ultrasound help…

This study is testing whether giving antibiotics and a special mouthwash before surgery can reduce the amount of bacteria inside oral cancer tumors. Researchers want to see if lowering these bacteria helps the body's immune system fight the cancer better. The trial involves 30 pa…

This study is testing a new, personalized treatment plan for people with oral cancer who have a high risk of the cancer returning. After initial surgery and radiation/chemotherapy, a blood test will check for leftover cancer cells. If the test is positive, patients will receive l…

This study is testing a new AI system that uses video to measure how well people can open their jaw and move their shoulder. Researchers will compare the AI's measurements to standard tools in 20 healthy adults and 20 oral cancer patients. The goal is to see if this simple, video…

This study aims to find the best pain relief combination for patients recovering from oral cancer surgery. Researchers will compare two different painkiller mixes given through patient-controlled pumps after surgery. They want to see which provides better pain control with fewer …

This study checks if the benefits of a special AI-guided physical therapy program last over time for people recovering from oral cancer. It follows 65 patients for 9 months after their therapy ends to see if they keep better jaw and shoulder movement, less pain, and a better qual…

This study is testing whether starting a special tongue-strengthening exercise program early after surgery can improve speech and swallowing for people with tongue cancer. The program uses a small biofeedback device called a Tongueometer to guide exercises. Researchers want to se…

This study is testing whether AI-guided physical therapy can help oral cancer patients maintain better movement and quality of life during treatment. One hundred newly diagnosed patients will either use a smartphone app that guides their jaw, neck, and shoulder exercises or recei…

This study is testing whether an AI-powered chatbot is a better teaching tool than traditional educational handouts for increasing knowledge about oral cancer. Researchers will enroll 60 African American adults from the Richmond area and randomly assign them to learn from either …

This study aims to understand why some oral cancers are more aggressive and how patients respond to treatment. Researchers will collect tissue samples and health data from 1000 adults with oral cancer or pre-cancer before, during, and after their standard treatments. The goal is …

This study aims to understand why oral cancer causes pain from pressure and stretching, like when talking or swallowing. Researchers will compare pain sensitivity in 40 oral cancer patients and 40 healthy volunteers. The goal is to gather knowledge that could lead to new pain tre…

This study aims to understand if changes in the natural bacteria in our mouth and gut (the microbiome) play a role in causing head and neck cancers. Researchers will collect saliva and stool samples from 60 people, including those with and without oral cancer, to analyze the bact…