Painless mouth scans could replace biopsies for oral cancer detection

This study compares two non-invasive techniques—a cell-collection brush test and a special microscope—to see if they can accurately detect precancerous and early cancerous spots in the mouth. Researchers will enroll 400 adults with visible mouth lesions. If successful, these methods could help doctors decide which lesions need a biopsy without cutting tissue, making screening easier and less painful.