ORAL CANCER

This study tests whether mixed reality (MR) technology can help surgeons remove oral cancer and rebuild the mouth more precisely. Thirty adults with oral cancer will be split into three groups: one using MR goggles, one using a 3D-printed guide, and one having standard surgery. T…

This study tests a new, low-cost handheld device that uses light therapy (photodynamic therapy) to treat pre-cancerous and early cancerous mouth lesions. The goal is to see if this treatment can destroy these lesions without needing surgery. The study will enroll 65 adults with h…

This study tests whether giving a short course of targeted radiation (SBRT) along with chemotherapy and immunotherapy before surgery can help people with advanced mouth or throat cancer live longer without the cancer coming back. About 184 adults with untreated, advanced oral or …

This study tests whether rinsing with hydrogen water can reduce mouth inflammation, pain, and improve healing in 36 adults after oral cancer surgery with free flap reconstruction. Participants will use hydrogen water mouth care for 7 days, and researchers will measure changes in …

This study tests whether a smartphone app with swallowing exercises can help people recover better after oral cancer surgery. About 72 adults in Taiwan will either get standard care or use the app for 12 weeks. Researchers will measure swallowing function, anxiety, and quality of…

This study looks at how the upper trapezius muscle changes in oral cancer patients who have had neck dissection and physical therapy. Researchers will use ultrasound to measure muscle size and thickness, and check how well patients can lift their arms. The goal is to see if ultra…

This early-stage study tests whether inhaling the cancer drug afatinib works as well as taking it by mouth. It involves 24 healthy adult smokers who will receive both forms in separate sessions. The goal is to measure drug levels in the blood and lungs, and check for side effects…