ORAL CANCER
Clinical trials for ORAL CANCER explained in plain language.
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Could an immunotherapy combo replace harsh chemo for head and neck cancer?
Disease control OngoingThis phase II trial tests whether combining the immunotherapy drug durvalumab (Imfinzi) with radiation therapy can effectively treat intermediate-risk head and neck cancer after surgery, while causing fewer serious side effects than the standard cisplatin-based chemo-radiation. T…
Matched conditions: ORAL CANCER
Phase: PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Could a Chemo-Immunotherapy cocktail spare head and neck cancer patients from radiation?
Disease control OngoingThis phase 2 trial tests a combination of two chemotherapy drugs (carboplatin and nab-paclitaxel) plus an immunotherapy drug (durvalumab) given before surgery for people with locally advanced head and neck cancer. The goal is to shrink or eliminate the tumor so that radiation—whi…
Matched conditions: ORAL CANCER
Phase: PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Immunotherapy may replace chemo in head and neck cancer trial
Disease control OngoingThis study tests whether the immunotherapy drug pembrolizumab (Keytruda) combined with radiation works better than the standard chemotherapy drug cisplatin with radiation for patients with a certain type of head and neck cancer (p16-positive). About 126 adults with advanced or in…
Matched conditions: ORAL CANCER
Phase: PHASE2 • Sponsor: Loren Mell, MD • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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New study tests safer pain relief for oral cancer patients
Symptom relief ENROLLING_BY_INVITATIONThis study compares two pain management strategies for adults with oral cancer who have moderate to severe pain. One group receives the opioid tramadol, while the other gets a combination of pregabalin and naproxen sodium. Over 7 days, researchers measure pain reduction, side eff…
Matched conditions: ORAL CANCER
Phase: NA • Sponsor: Mayo Hospital Lahore • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Can a smartphone app help oral cancer patients recover faster?
Symptom relief OngoingThis study tests whether a remote rehabilitation app can improve shoulder and neck recovery in oral cancer patients who had neck dissection surgery. 80 patients are randomly assigned to either standard home exercise materials or the app, which provides daily reminders and lets pa…
Matched conditions: ORAL CANCER
Phase: NA • Sponsor: Pai Pang • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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New online program aims to empower oral cancer survivors
Symptom relief OngoingThis study tests an online program called Empowered Survivor, designed to help people who have had oral or throat cancer feel more confident managing their health after treatment. Researchers are comparing it to a free online tool already available for cancer survivors. The goal …
Matched conditions: ORAL CANCER
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Can strawberry gummies fight gum disease and oral cancer?
Knowledge-focused OngoingThis early-phase study tests whether strawberry gummies can improve oral health in 36 adults, including smokers and non-smokers. Participants eat two types of gummies (real strawberry or placebo) four times daily for a week. Researchers measure how the body absorbs strawberry com…
Matched conditions: ORAL CANCER
Phase: PHASE1 • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC