OPIOID USE DISORDER
Clinical trials for OPIOID USE DISORDER explained in plain language.
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App aims to boost opioid treatment start rates from ER
Disease control TerminatedThis study tested a mobile app called OARSCM that uses rewards to encourage people with opioid use disorder to start and stay with medication treatment (Suboxone) after leaving the emergency room or hospital. The study enrolled 41 adults from two hospitals. The study was terminat…
Matched conditions: OPIOID USE DISORDER
Phase: NA • Sponsor: Q2i, LLC • Aim: Disease control
Last updated May 16, 2026 23:47 UTC
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New approach to starting opioid addiction treatment avoids withdrawal
Disease control TerminatedThis study tested a new method for starting buprenorphine (a medication for opioid use disorder) that avoids the usual withdrawal symptoms. Instead of stopping all opioids first, patients started with very low doses of buprenorphine while still taking their regular opioids. The s…
Matched conditions: OPIOID USE DISORDER
Phase: PHASE4 • Sponsor: Montefiore Medical Center • Aim: Disease control
Last updated May 16, 2026 23:38 UTC
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Can a different opioid drug help pain patients break free from dependence?
Disease control TerminatedThis small study aimed to see if buprenorphine could control chronic pain and prevent withdrawal in people already dependent on opioid pain medications. Only 4 people enrolled before the study was stopped. The goal was to improve pain and quality of life without withdrawal sympto…
Matched conditions: OPIOID USE DISORDER
Phase: PHASE4 • Sponsor: Theresa Jacob, PhD, MPH • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Restless legs drug may ease opioid withdrawal, study halted early
Symptom relief TerminatedThis study tested whether pramipexole, a drug for restless legs syndrome, could reduce both restless legs and ongoing withdrawal symptoms in people recovering from opioid use disorder. The goal was to help them stay in treatment. The study was terminated early, so results are lim…
Matched conditions: OPIOID USE DISORDER
Phase: PHASE2, PHASE3 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated May 16, 2026 23:48 UTC
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Can a simple device replace drugs for opioid withdrawal?
Symptom relief TerminatedThis study tested a device called Bridge to see if it could reduce opioid withdrawal symptoms. Researchers compared the real device to a fake one in 13 adults with opioid use disorder. The goal was to find a non-drug way to help people feel better during withdrawal.
Matched conditions: OPIOID USE DISORDER
Phase: NA • Sponsor: Masimo Corporation • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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HIV and opioid treatment study halted: what we know
Knowledge-focused TerminatedThis study aimed to understand how different medications for opioid use disorder (like methadone or buprenorphine) impact the immune system in people with HIV. Researchers wanted to see if these drugs could reduce gut-related inflammation and improve immune recovery. The study wa…
Matched conditions: OPIOID USE DISORDER
Phase: PHASE2 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated May 12, 2026 13:42 UTC
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Opioid choice study ends early after just 2 participants
Knowledge-focused TerminatedThis study aimed to understand how withdrawal symptoms and drug-related cues influence decision-making in people with opioid use disorder. Participants completed choice tasks to see how they weighed high-probability rewards. The study was terminated early and only enrolled 2 peop…
Matched conditions: OPIOID USE DISORDER
Phase: EARLY_PHASE1 • Sponsor: Joshua A. Lile, Ph.D. • Aim: Knowledge-focused
Last updated May 07, 2026 18:41 UTC