Restless legs drug may ease opioid withdrawal, study halted early

NCT ID NCT04759703

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 26 times

Summary

This study tested whether pramipexole, a drug for restless legs syndrome, could reduce both restless legs and ongoing withdrawal symptoms in people recovering from opioid use disorder. The goal was to help them stay in treatment. The study was terminated early, so results are limited.

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Contacts and locations

Locations

  • Gavin Foundation Clinical Stabilization Services

    Quincy, Massachusetts, 02170, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.