OBESITY AND OVERWEIGHT
Clinical trials for OBESITY AND OVERWEIGHT explained in plain language.
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New weekly shot shows promise for obesity treatment
Disease control CompletedThis study tested a new medicine called MET097, given as a weekly injection, to help adults with overweight or obesity lose weight. The trial involved 120 otherwise healthy participants and looked at safety, how the drug works in the body, and weight change over 12 weeks. Some pa…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: PHASE1, PHASE2 • Sponsor: Metsera, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated May 17, 2026 02:18 UTC
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Can a polyphenol drink help shed pounds? new study investigates
Disease control CompletedThis completed study tested a polyphenol-enriched product in 70 overweight or obese adults to see if it could help with weight loss, fat reduction, and improve metabolic health markers like insulin sensitivity. Participants took the product or a placebo for a period, and research…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: Carmen Lucas Abellán • Aim: Disease control
Last updated May 17, 2026 02:07 UTC
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Weight loss showdown: study pits top programs against each other
Disease control CompletedThis study looked at how well three different commercial weight management programs help adults with overweight or obesity lose weight. Over 450 people took part, and the main goal was to see how much weight they lost after 12 weeks. The study also checked changes in physical act…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: WW International Inc • Aim: Disease control
Last updated May 14, 2026 12:01 UTC
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New supplement shows promise for shedding body fat in overweight adults
Disease control CompletedThis study tested whether a supplement called BK329 can safely reduce body fat in adults who are overweight or obese. One hundred participants took either BK329 or a placebo daily for 12 weeks. Researchers measured changes in total body fat, weight, and other health markers using…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: Pusan National University Yangsan Hospital • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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Rice swap shows promise for prediabetes in small study
Disease control CompletedThis study looked at whether eating sorghum rice instead of white rice for one week could improve health markers in people with prediabetes. Twenty-six police officers with prediabetes were split into two groups: one ate sorghum rice, the other white rice. Researchers measured ch…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: Dr. Soetomo General Hospital • Aim: Disease control
Last updated May 07, 2026 18:38 UTC
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AI coach helps nurses beat emotional eating in new study
Symptom relief CompletedThis study tested whether a ChatGPT-supported online group program could help overweight female nurses manage emotional and uncontrolled eating. 44 nurses participated in online sessions guided by a facilitator with AI support. The goal was to improve eating behaviors and body im…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: Dokuz Eylul University • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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New weight loss drug shows promise in early human trial
Symptom relief CompletedThis early-stage study tested a single dose of HDM1005 in 65 healthy adults to check its safety and how the body processes it. Researchers also looked at changes in weight and other health markers. The goal is to see if this drug could help with weight management in the future.
Matched conditions: OBESITY AND OVERWEIGHT
Phase: PHASE1 • Sponsor: Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. • Aim: Symptom relief
Last updated May 12, 2026 13:42 UTC
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Diet study reveals how weight loss changes gene activity in overweight adults
Knowledge-focused CompletedThis study looked at how a low-calorie diet changes the activity of certain genes in white blood cells and affects heart health markers in 60 overweight adults with high triglycerides. Researchers measured gene expression and blood fat levels to compare people who lost a lot of w…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: Shahid Beheshti University of Medical Sciences • Aim: Knowledge-focused
Last updated May 17, 2026 02:18 UTC
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Surgery for severe obesity may change appetite hormone levels
Knowledge-focused CompletedThis study looked at 36 adults with severe obesity who had laparoscopic sleeve gastrectomy, a type of weight-loss surgery. Researchers measured blood levels of Phoenixin-14, a hormone linked to appetite control, before and after surgery. The goal was to see if the surgery changes…
Matched conditions: OBESITY AND OVERWEIGHT
Sponsor: Kahramanmaras Sutcu Imam University • Aim: Knowledge-focused
Last updated May 17, 2026 02:07 UTC
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Pub quiz reveals: calorie labels may curb drinking
Knowledge-focused CompletedThis study looked at whether showing calorie information on alcohol or changing serving sizes can help people drink less. Over 300 adults who drink regularly took part in a real-world pub quiz. Researchers measured how much alcohol and calories they consumed during the evening.
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: University of Liverpool • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Processed food shock: even one meal alters your stress hormone!
Knowledge-focused CompletedThis study looked at how eating ultra-processed foods versus unprocessed foods affects the stress hormone cortisol in healthy men. Twenty volunteers ate two different meals with similar calories and nutrients, and their blood cortisol levels were measured before and after eating.…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: Eleonora Seelig • Aim: Knowledge-focused
Last updated May 11, 2026 20:52 UTC