Calorie cutting may switch on genes that control fat and appetite

NCT ID NCT07012226

First seen Jan 03, 2026 · Last updated May 23, 2026 · Updated 21 times

Summary

This study looked at how a low-calorie diet changes the activity of two genes (SIRT1 and leptin receptor) in white blood cells of 60 adults who are overweight and have high triglycerides. Researchers measured these gene changes along with blood fats, hormones, and inflammation markers. The goal was to understand why some people lose more weight than others on the same diet.

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Contacts and locations

Locations

  • Nutrition Clinic located in the Faculty of Nutrition Sciences, Shahid Beheshti University of Medical Sciences

    Tehran, Tehran Province, Iran

Conditions

Explore the condition pages connected to this study.