OBESITY AND OVERWEIGHT
Clinical trials for OBESITY AND OVERWEIGHT explained in plain language.
Never miss a new study
Get alerted when new OBESITY AND OVERWEIGHT trials appear
Sign up with your email to follow new studies for OBESITY AND OVERWEIGHT, keep track of the ones that matter, and come back to a personal dashboard instead of checking manually.
By submitting, you agree to our Terms of use
-
New Weight-Loss shot shows promise in large trial
Disease control OngoingThis study tests an experimental injection called efsubaglutide alfa to help overweight and obese adults lose weight. About 1,000 participants will receive either the drug or a placebo for up to 48 weeks. The main goal is to see how much weight they lose and if the treatment is s…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: PHASE2, PHASE3 • Sponsor: Shanghai Yinnuo Pharmaceutical Technology Co., Ltd. • Aim: Disease control
Last updated May 17, 2026 02:06 UTC
-
New obesity drug HCR-188 enters first human safety trial
Disease control TerminatedThis early-stage study tests a new drug called HCR-188 in 48 overweight or obese adults to see if it is safe and how the body processes it. Participants receive either the drug or a placebo as injections. The goal is to check for side effects and gather initial information, not t…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: EARLY_PHASE1 • Sponsor: Helicore Biopharma, Inc. • Aim: Disease control
Last updated May 17, 2026 02:03 UTC
-
Natural plant extracts show promise for appetite control and weight loss
Disease control OngoingThis study tests whether two plant extracts, Cissus quadrangularis and Dichrostachys glomerata, can help overweight and obese adults manage their weight. The extracts aim to boost a natural hormone (GLP-1) that controls appetite and reduce an enzyme that breaks it down. Researche…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: PHASE1, PHASE2 • Sponsor: University of Yaounde 1 • Aim: Disease control
Last updated May 17, 2026 02:02 UTC
-
New weekly shot shows promise for obesity treatment in early trial
Disease control OngoingThis study tests a new medicine called MET233, given as a weekly injection, to see if it is safe and helps with weight loss. It includes 120 adults who are overweight or have obesity but are otherwise healthy. Participants receive either the drug or a placebo for up to 12 weeks, …
Matched conditions: OBESITY AND OVERWEIGHT
Phase: PHASE1, PHASE2 • Sponsor: Metsera, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated May 13, 2026 16:00 UTC
-
Smart diet study aims to outsmart prediabetes in people with disabilities
Disease control OngoingThis study tests different weight loss plans for 30 adults with prediabetes and physical disabilities. Participants first try either a high or low carbohydrate diet. After 4 weeks, those who lose less than 2.5% of their body weight get extra help, like exercise coaching or time-r…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
-
Can a Plant-Powered diet or special supplements help you lose weight?
Disease control OngoingThis study is testing whether getting more polyphenols—natural compounds found in plants—can help people lose weight and improve heart health. For 12 weeks, 99 adults with overweight or obesity will either follow a special plant-based diet, take polyphenol supplements, or follow …
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: Universidad Catolica de Temuco • Aim: Disease control
Last updated Apr 22, 2026 15:58 UTC
-
Can a natural hormone curb food cravings in the brain?
Knowledge-focused OngoingThis study looks at whether a natural hormone called LEAP2 can lower brain activity in response to food pictures in people with obesity. Twenty-eight men with a BMI between 30 and 50 will receive either LEAP2 or a placebo on two separate days and undergo brain scans. The goal is …
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: University Hospital, Gentofte, Copenhagen • Aim: Knowledge-focused
Last updated May 17, 2026 02:07 UTC
-
Scientists peek inside brown fat to see how it responds to calorie cutting
Knowledge-focused OngoingThis study looks at how brown fat—a type of body fat that burns energy—adapts when people with obesity lose weight through a calorie-restricted diet. Thirty young adults will either maintain their weight or lose 8-10% over 12-16 weeks. Researchers will use scans and tissue sample…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: Universidad de Granada • Aim: Knowledge-focused
Last updated May 17, 2026 02:02 UTC