New weekly shot could help shed pounds in major obesity trial

NCT ID NCT07311850

Recruiting now Disease control Sponsor: Metsera, a wholly owned subsidiary of Pfizer Source: ClinicalTrials.gov ↗

First seen Jan 10, 2026 · Last updated May 05, 2026 · Updated 14 times

Summary

This study tests a new once-weekly injection called MET097 in 3500 adults with obesity or overweight who also have weight-related health issues like high blood pressure or sleep apnea. The goal is to see how much weight participants lose over 64 weeks and whether the treatment is safe. People with diabetes are not eligible for this trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Locations

4 Life EOOD
NOT_YET_RECRUITING

Burgas, 8018, Bulgaria
Advanced Clinical Research
RECRUITING

Miami, Florida, 33156, United States
Agentura science pro s.r.o.
NOT_YET_RECRUITING

Olomouc, 77900, Czechia
Alliance Research Institute
RECRUITING

Canoga Park, California, 91304, United States
AmBeNet GmbH
NOT_YET_RECRUITING

Leipzig, 4107, Germany
Bodyline Medical Clinic Crosby
NOT_YET_RECRUITING

Liverpool, L224QQ, United Kingdom
Bodyline Medical Clinic St Helens
NOT_YET_RECRUITING

St Helens, Liverpool, WA9 1AF, United Kingdom
Bodyline Medical Clinic Stoke on Trent
NOT_YET_RECRUITING

Stoke-on-Trent, ST1 5TL, United Kingdom
Bodyline Medical Clinic Warrington
NOT_YET_RECRUITING

Warrington, Cheshire EAST, WA1 3TZ, United Kingdom
Bodyline Medical Research Openshaw
NOT_YET_RECRUITING

Openshaw, Manchester, M11 1AA, United Kingdom
Boots Birmingham
NOT_YET_RECRUITING

Birmingham, B4 7TA, United Kingdom
Boots Brighton
NOT_YET_RECRUITING

Brighton, EAST Sussex, BN1 2BE, United Kingdom
Boots Nottingham
NOT_YET_RECRUITING

Nottingham, Nottinghamshire, NG1 3QS, United Kingdom
Boots Peterborough
NOT_YET_RECRUITING

Peterborough, Cambridgeshire, PE1 1NW, United Kingdom
C-health Research
NOT_YET_RECRUITING

Edmonton, Alberta, T6H 2L4, Canada
CCR Ostrava
NOT_YET_RECRUITING

Ostrava, 702 00, Czechia
CDG Studienambulanz Hartard
NOT_YET_RECRUITING

Munich, Bavaria, 80809, Germany
CEDIC
NOT_YET_RECRUITING

Buenos Aires, C1060, Argentina
CIAD Moron
NOT_YET_RECRUITING

Morón, B1708EPE, Argentina
CIDIM
NOT_YET_RECRUITING

Córdoba, X5000AVE, Argentina
CINME
NOT_YET_RECRUITING

Buenos Aires, C1056ABI, Argentina
CIPADI - Centro Integral de Prevencion Y Atencion en Diabetes
NOT_YET_RECRUITING

Godoy Cruz, M5501ARP, Argentina
Cardio D&R Košice
NOT_YET_RECRUITING

Košice, 040 22, Slovakia
Cedar Health Research
NOT_YET_RECRUITING

Dallas, Texas, 75251, United States
CenExcel Rocky Mountain Clinical Research, LLC
RECRUITING

Englewood, Colorado, 80113, United States
CenExel CBH Health
RECRUITING

Gaithersburg, Maryland, 20877, United States
CenExel FCR - ForCare Clinical Research
RECRUITING

Tampa, Florida, 33613, United States
CenExel HRI - Hassman Research Institute
RECRUITING

Marlton, New Jersey, 08053, United States
CenExel iResearch, LLC
RECRUITING

Savannah, Georgia, 31405, United States
Centricity Research Etobicoke Endocrinology
NOT_YET_RECRUITING

Etobicoke, Ontario, M9R 4E1, Canada
Centro Medico Privado de Reumatologia
NOT_YET_RECRUITING

San Miguel de Tucumán, T4000AXA, Argentina
Centro Medico Viamonte
NOT_YET_RECRUITING

Buenos Aires, C1120AAC, Argentina
Centru Medical "GRANDMED"
NOT_YET_RECRUITING

Oradea, Romania
Centrul Medical Mediab - Mediab Srl
NOT_YET_RECRUITING

Târgu Mureş, Romania
Centrum Badan Klinicznych PI-House Sp. z o.o.
NOT_YET_RECRUITING

Gdansk, 80-546, Poland
Centrum Medyczne Pratia Gdynia
NOT_YET_RECRUITING

Gdynia, 81-338, Poland
Centrum Medyczne Pratia Katowice
NOT_YET_RECRUITING

Katowice, 40-081, Poland
Centrum Terapii Współczesnej J.M. Jasnorzewska Spółka Komandytowo-Akcyjna
NOT_YET_RECRUITING

Lodz, 90-338, Poland
Centrum medyczne Pratia Bydgoszcz
NOT_YET_RECRUITING

Bydgoszcz, 85-796, Poland
Civia Health Goodlettsville
RECRUITING

Goodlettsville, Tennessee, 37072, United States
Civia Health Independence
NOT_YET_RECRUITING

Independence, Missouri, 64055, United States
Civia Health Memphis
NOT_YET_RECRUITING

Memphis, Tennessee, 38117, United States
Civia Health Nashville
RECRUITING

La Vergne, Tennessee, 37086, United States
Civia Health Shelby
NOT_YET_RECRUITING

Shelby, Michigan, 48315, United States
Civia Health St. Louis
NOT_YET_RECRUITING

Creve Coeur, Missouri, 63141, United States
Civia Health Sunderland
NOT_YET_RECRUITING

Hendon, CITY of Sunderland, SR1 1PB, United Kingdom
Clifton Medical Centre
NOT_YET_RECRUITING

Rotherham, S65 2EN, United Kingdom
Clinica Privada Velez Sarsfield
NOT_YET_RECRUITING

Córdoba, 5000, Argentina
Clinical Innovations, Inc dba CITrials
RECRUITING

Riverside, California, 92506, United States
Clinical Research Professionals
RECRUITING

Chesterfield, Missouri, 63005, United States
Collaborative Neuroscience Research, LLC
RECRUITING

Torrance, California, 90504, United States
DANES Medical Centre
NOT_YET_RECRUITING

Northampton, NN1 5PH, United Kingdom
DIABEDA s.r.o.
NOT_YET_RECRUITING

Bratislava, Bratislava, Slovakia
DZHW
NOT_YET_RECRUITING

Hamburg, 22607, Germany
Dallas Clinical Research Center (Pillar Clinical Research)
RECRUITING

Richardson, Texas, 75080, United States
DelRicht Research @ Springer Wellness and Restorative Health
RECRUITING

Atlanta, Georgia, 30329, United States
Diabetes Studienzentrum Wilhelmsburg
NOT_YET_RECRUITING

Hamburg, 21109, Germany
Diabetespraxis Dr. Braun
NOT_YET_RECRUITING

Berlin, 13187, Germany
Diagnostic Consultative Center Aleksandrovska
NOT_YET_RECRUITING

Sofia, 1431, Bulgaria
ETG Siedlce
NOT_YET_RECRUITING

Siedlce, 08-110, Poland
Ecg Médica S.L.
NOT_YET_RECRUITING

Valencia, 46015, Spain
Edumed s.r.o.
NOT_YET_RECRUITING

Náchod, 54701, Czechia
Ekamed Sp. z o. o.
NOT_YET_RECRUITING

Lublin, 20-718, Poland
Etg Warszawa
NOT_YET_RECRUITING

Warsaw, 02-677, Poland
Eximia EquiHealth Research
RECRUITING

Durham, North Carolina, 27704, United States
Fakultní nemocnice Královské Vinohrady
NOT_YET_RECRUITING

Prague, 100 34, Czechia
Forum Austin (Civia Health)
RECRUITING

Austin, Texas, 78578, United States
Forum Health Cary
RECRUITING

Cary, North Carolina, 27511, United States
Fundatia Dr Victor Babes
NOT_YET_RECRUITING

Bucharest, 30303, Romania
Future Medical Research (Civia Health)
RECRUITING

Longwood, Florida, 32750, United States
FutureMeds (Birmingham)
NOT_YET_RECRUITING

Birmingham, B21 9RY, United Kingdom
FutureMeds Berlin
NOT_YET_RECRUITING

Berlin, 10629, Germany
FutureMeds Frankfurt/Offenbach
NOT_YET_RECRUITING

Offenbach, 63065, Germany
FutureMeds Gdynia
NOT_YET_RECRUITING

Gdynia, 81-384, Poland
FutureMeds Glasgow McCafferty House
NOT_YET_RECRUITING

Glasgow, Scotland, G20 7BE, United Kingdom
FutureMeds Krakow
NOT_YET_RECRUITING

Krakow, 31-501, Poland
FutureMeds Liverpool
NOT_YET_RECRUITING

Bromborough, CH62 6EE, United Kingdom
FutureMeds Lodz
NOT_YET_RECRUITING

Lodz, 91-393, Poland
FutureMeds London
NOT_YET_RECRUITING

London, NW10 2PB, United Kingdom
FutureMeds Newcastle
NOT_YET_RECRUITING

Newcastle upon Tyne, NE6 1SG, United Kingdom
FutureMeds Olsztyn
NOT_YET_RECRUITING

Olsztyn, 10-165, Poland
FutureMeds Plovdiv
NOT_YET_RECRUITING

Plovdiv, 4000, Bulgaria
FutureMeds Warszawa Centrum
NOT_YET_RECRUITING

Warsaw, 00-215, Poland
FutureMeds Warszawa Targowek
NOT_YET_RECRUITING

Warszawa Targowek, 03-291, Poland
FutureMeds Wroclaw
NOT_YET_RECRUITING

Wroclaw, 53-673, Poland
Futuremeds S.R.L., Brasov
NOT_YET_RECRUITING

Brasov, Romania
Futuremeds S.R.L., Craiova
NOT_YET_RECRUITING

Craiova, Romania
Futuremeds S.R.L., Galati
NOT_YET_RECRUITING

Galati, Romania
Futuremeds Spain Cadiz
NOT_YET_RECRUITING

Chiclana de la Frontera, 11139, Spain
Futuremeds Spain Madrid
NOT_YET_RECRUITING

Madrid, 28003, Spain
Futuremeds Spain Sevilla
NOT_YET_RECRUITING

Seville, 41012, Spain
Futuremeds Teesside Middlefield Centre University Hospital of North Tees
NOT_YET_RECRUITING

Teeside, TS19 8PE, United Kingdom
GLRI El Paso Research
RECRUITING

El Paso, Texas, 79936, United States
Gemeinschaftspraxis PD Dr. med. habil. Holger Kittner & Dr. Hartig
NOT_YET_RECRUITING

Naunhof, 4683, Germany
Headlands Research
RECRUITING

Scottsdale, Arizona, 85260, United States
Hightech Medical Services S.R.L (Centrul pentru Studiul Metabolismului)
NOT_YET_RECRUITING

Bucharest, 011053, Romania
Hospital Universitari Son Espases
NOT_YET_RECRUITING

Palma de Mallorca, 07120, Spain
Hospital Universitari Vall d'Hebron
NOT_YET_RECRUITING

Barcelona, 08035, Spain
Hospital Universitario Torrecárdenas (CPE Bola Azul)
NOT_YET_RECRUITING

Almería, 04009, Spain
Hospital Universitario Virgen de la Victoria
NOT_YET_RECRUITING

Málaga, Málaga, 29010, Spain
Hospital Virgen del Camino
NOT_YET_RECRUITING

Sanlúcar de Barrameda, 11540, Spain
Hospital Vithas Sevilla
NOT_YET_RECRUITING

Castilleja de la Cuesta, 41950, Spain
IDFM GmbH
NOT_YET_RECRUITING

Münster, 48145, Germany
IIC Mar del Plata
NOT_YET_RECRUITING

Mar del Plata, 7600, Argentina
IRMED
NOT_YET_RECRUITING

Piotrkow Trybunalski, 97-300, Poland
Instituto Medico Catamarca (IMEC)
NOT_YET_RECRUITING

Santa Fe, S2000, Argentina
Instituto de Investigaciones Clinicas Cordoba
NOT_YET_RECRUITING

Córdoba, X5000AAW, Argentina
Institutul Clinic Fundeni
NOT_YET_RECRUITING

Bucharest, Romania
Institutul National de Endocrinologie "C.I. Parhon"
NOT_YET_RECRUITING

Bucharest, Romania
Instytut Diabetologii.sp.z.o.o.
NOT_YET_RECRUITING

Warsaw, 02-117, Poland
JAL s.r.o.
NOT_YET_RECRUITING

Trnava, 91701, Slovakia
Kardiologische Praxis Dr. med. univ. Wolfgang Jungmair
NOT_YET_RECRUITING

Bad Homburg, 61348, Germany
Kiltearn Medical Centre
NOT_YET_RECRUITING

Nantwich, CW5 5NX, United Kingdom
Klinische Forschung Berlin-Mitte GmbH
NOT_YET_RECRUITING

Berlin, 10117, Germany
Klinische Forschung Hamburg GmbH / Pratia
NOT_YET_RECRUITING

Hamburg, 20253, Germany
Klinische Forschung Karlsruhe GmbH
NOT_YET_RECRUITING

Karlsruhe, 76137, Germany
LMC Diabetes & Endocrinology - Bayview (Centricity Research Toronto LMC Multispecialty)
NOT_YET_RECRUITING

Toronto, Ontario, M4G 3E8, Canada
MC Nevromedics Ltd.
NOT_YET_RECRUITING

Veliko Tarnovo, 5005, Bulgaria
MC Nova Clinic
NOT_YET_RECRUITING

Varna, 9000, Bulgaria
MEDI-DIA s.r.o.
NOT_YET_RECRUITING

Prešov, 080 01, Slovakia
MHAT Botevgrad
NOT_YET_RECRUITING

Botevgrad, 2140, Bulgaria
MHAT Sveta Karidad EAD
NOT_YET_RECRUITING

Plovdiv, 4004, Bulgaria
Manna Research Mirabel
NOT_YET_RECRUITING

Mirabel, Quebec, J7J 2K8, Canada
Medical Center - Clinic Nova
NOT_YET_RECRUITING

Varna, Bulgaria
Medical Center Berbatov
NOT_YET_RECRUITING

Yambol, 8600, Bulgaria
Medical Center Hera EOOD
NOT_YET_RECRUITING

Sofia, 1710, Bulgaria
Medical Center New Polyclinic Gabrovo Ltd.
NOT_YET_RECRUITING

Gabrovo, 5300, Bulgaria
Medical Center Zdrave 1
NOT_YET_RECRUITING

Kozloduy, 3320, Bulgaria
Medical Centre Pratia Clinic EOOD
NOT_YET_RECRUITING

Varna, 9020, Bulgaria
Medical group Kosice s.r.o.
NOT_YET_RECRUITING

Košice, 04001, Slovakia
Medicome Sp. z o.o. Oświęcimskie Centrum Badań Klinicznych
NOT_YET_RECRUITING

Oświęcim, 32-600, Poland
Medislim GmbH
NOT_YET_RECRUITING

Weinheim, 69469, Germany
Medispektrum
NOT_YET_RECRUITING

Bratislava, 85101, Slovakia
Medivasa sro
NOT_YET_RECRUITING

Žilina, 01001, Slovakia
Medizentrum Essen Borbeck
NOT_YET_RECRUITING

Essen, 45355, Germany
Metabolica Sp. z o.o., NZOZ METABOLICA Ośrodek Badań Klinicznych
NOT_YET_RECRUITING

Tarnów, 33-100, Poland
Minimed S.R.L.
NOT_YET_RECRUITING

Bacau, Romania
Multiprofile Hospital for Active Treatment Dobrich AD (MHAT Dobrich AD)
NOT_YET_RECRUITING

Dobrich, 9300, Bulgaria
NZOZ Centrum Medyczne KERmed
NOT_YET_RECRUITING

Bydgoszcz, 85-231, Poland
Nemocnice Jihlava
NOT_YET_RECRUITING

Jihlava, 58601, Czechia
Nuevas Tecnologías en Diabetes y Endocrinología S.L.
NOT_YET_RECRUITING

Seville, 41003, Spain
Oviedo Medical Research
RECRUITING

Oviedo, Florida, 32765, United States
Pantheon Clinical Research
RECRUITING

Bountiful, Utah, 84010, United States
Panthera Biopartners Limited - Enfield
NOT_YET_RECRUITING

Enfield, EN3 4GS, United Kingdom
Panthera Biopartners Limited - Glasgow
NOT_YET_RECRUITING

Glasgow, G51 4TY, United Kingdom
Panthera Biopartners Limited - Preston
NOT_YET_RECRUITING

Preston, PR2 9QB, United Kingdom
Panthera Biopartners Limited - Rochdale
NOT_YET_RECRUITING

Rochdale, OL11 4AU, United Kingdom
Panthera Biopartners Limited - Sheffield
NOT_YET_RECRUITING

Sheffield, S2 5FX, United Kingdom
Panthera Biopartners Limited - York
NOT_YET_RECRUITING

York, YO24 4LJ, United Kingdom
Peninsula Headlands LLC
RECRUITING

Rolling Hills, California, 90274, United States
Poliklinika Váš Lekár
NOT_YET_RECRUITING

Bratislava - Ružinov, 91109, Slovakia
Praktyka Lekarska Ewa Krzyzagorska
NOT_YET_RECRUITING

Poznan, 61-655, Poland
Pratia
NOT_YET_RECRUITING

Dresden, 1069, Germany
Pratia Brno,s.r.o
NOT_YET_RECRUITING

Brno, 60200, Czechia
Pratia Chojnice
NOT_YET_RECRUITING

Chojnice, 89-600, Poland
Pratia Pardubice
NOT_YET_RECRUITING

Pardubice, 53002, Czechia
Praxis Reinfeld Mitte
NOT_YET_RECRUITING

Holstein, 23858, Germany
Praxis am Markt - Dr. Bernd Becker
NOT_YET_RECRUITING

Essen, 45355, Germany
Prevencia - 2000 - Medical Center for Prehospital Medical Care OOD
NOT_YET_RECRUITING

Stara Zagora, 6000, Bulgaria
PreventaMed s.r.o.
NOT_YET_RECRUITING

Olomouc, 77900, Czechia
Primary Care Research (Civia Health)
RECRUITING

Papillion, Nebraska, 68046, United States
Quality Clinical Research Inc
RECRUITING

Omaha, Nebraska, 68114, United States
ResTrial s.r.o.
NOT_YET_RECRUITING

Prague, 18100, Czechia
Research Centers of America
RECRUITING

Hollywood, Florida, 33024, United States
Sandbach GPs
NOT_YET_RECRUITING

Sandbach, CW11 1EQ, United Kingdom
Santa Sp. z.o.o.
NOT_YET_RECRUITING

Lodz, 90-302, Poland
Sc Gensan Srl/Policlinica Astra
NOT_YET_RECRUITING

Sibiu, 550371, Romania
Southmead Hospital
NOT_YET_RECRUITING

Bristol, BS10 5NB, United Kingdom
Staploe Medical Centre
NOT_YET_RECRUITING

Soham, ELY CB75JD, United Kingdom
Studienzentrum FMZ Radowsky
NOT_YET_RECRUITING

Leipzig, Saxony, 4179, Germany
Summit Headlands LLC
RECRUITING

Portland, Oregon, 97210, United States
Synergy Medical Clinic
NOT_YET_RECRUITING

Sherwood Park, Alberta, T8H 0N2, Canada
Synexus Polska Sp z o.o.
NOT_YET_RECRUITING

Gdansk, 80-382, Poland
Synexus Polska Sp. Z O.O. Oddzial W Katowicach
NOT_YET_RECRUITING

Katowice, 40-040, Poland
Synexus Polska Sp. z o.o. Oddzial w Gdyni
NOT_YET_RECRUITING

Gdynia, 81-537, Poland
Synexus Polska Sp. z o.o., Oddzial w Czestochowie
NOT_YET_RECRUITING

Częstochowa, 42-202, Poland
Synexus Polska Sp. z o.o., Oddzial w Lodzi
NOT_YET_RECRUITING

Lodz, 90-127, Poland
Synexus Polska Sp. z o.o., Oddzial w Warszawie
NOT_YET_RECRUITING

Warsaw, 02-672, Poland
Synexus Polska Sp. z o.o., Oddział w Poznaniu
NOT_YET_RECRUITING

Poznan, 60-702, Poland
Synexus Polska Sp. z o.o., Oddział we Wrocławiu
NOT_YET_RECRUITING

Wroclaw, 50-381, Poland
Synexus/Trialmed Cardiff
NOT_YET_RECRUITING

Cardiff, CF15 9SS, United Kingdom
Synexus/Trialmed Glasgow
NOT_YET_RECRUITING

Bellshill, ML4 3NJ, United Kingdom
Synexus/Trialmed Manchester
NOT_YET_RECRUITING

Manchester, M15 6SE, United Kingdom
Synexus/Trialmed Midlands
NOT_YET_RECRUITING

Birmingham, B15 2 SQ, United Kingdom
Synexus/Trialmed Prague
NOT_YET_RECRUITING

Prague, 120 00, Czechia
TMA Headlands LLC
RECRUITING

Wilmington, North Carolina, 28403, United States
Tatratrial s.r.o.
NOT_YET_RECRUITING

Rožňava, 048 01, Slovakia
The Wharton Medical Clinic Clinical Trials Inc
NOT_YET_RECRUITING

Hamilton, Ontario, L8L 5G8, Canada
Trialmed CRS
NOT_YET_RECRUITING

Piotrkow Trybunalski, 97-300, Poland
Tribe Clinical Research, LLC
RECRUITING

Greenville, South Carolina, 29607, United States
Tribe Clinical Research, LLC
RECRUITING

Spartanburg, South Carolina, 29301, United States
UMHAT "Prof. Dr. Stoyan Kirkovich"AD
NOT_YET_RECRUITING

Stara Zagora, 6003, Bulgaria
Velocity Clinical Research Germany, Berlin
NOT_YET_RECRUITING

Berlin, 12205, Germany
Zdrowie Osteo Medic sc L i A Racewicz, A i J Supronik
NOT_YET_RECRUITING

Bialystok, 15-351, Poland
Zentrum fuer klinische Forschung Koeln Duennwald
NOT_YET_RECRUITING

Kaln, 51069, Germany
Zentrum für kliniche Studien Allgäu-Oberschwaben
NOT_YET_RECRUITING

Wangen, 88239, Germany

Conditions

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OBESITY AND OVERWEIGHT