New weekly shot could help shed pounds in major obesity trial

NCT ID NCT07311850

Recruiting now Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This large phase 3 trial is testing a new once-weekly injection called MET097 for weight loss in 3501 adults with obesity or overweight (but without diabetes). Participants will receive either the drug or a placebo for up to 84 weeks. The main goal is to see how much weight people lose after 64 weeks of treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MET097 (a once-weekly injection that mimics a natural hormone to help with weight loss)

What this could lead to

If it works, this could offer a new, convenient once-weekly treatment option for significant and sustained weight loss in people with obesity or overweight.

What could go wrong

This is a phase 3 trial, but results are not yet known. Weight loss may be modest for some, and side effects like nausea or rare thyroid tumors are possible. It is not a cure for obesity.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY AND OVERWEIGHT

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Advanced Clinical Research
RECRUITING

Miami, Florida, 33156, United States
Agentura science pro s.r.o.
RECRUITING

Olomouc, 77900, Czechia
Alliance Research Institute
RECRUITING

Canoga Park, California, 91304, United States
AmBeNet GmbH
RECRUITING

Leipzig, 4107, Germany
Ashfields Primary Care Center
RECRUITING

Sandbach, Cheshire, CW11 1EQ, United Kingdom
Bodyline Medical Clinic Warrington Civia Health
RECRUITING

Paddington, WA1 3TZ, United Kingdom
Bodyline Medical Clinic, Crosby Civia Health
RECRUITING

Liverpool, L22 4QQ, United Kingdom
Bodyline Medical Clinic, St Helens Civia Health
RECRUITING

St Helens, WA9 1AF, United Kingdom
Bodyline Medical Clinic, Stoke-on-Trent Civia Health
RECRUITING

Stoke-on-Trent, ST1 5TL, United Kingdom
CCR Ostrava
RECRUITING

Ostrava, 702 00, Czechia
CDG Studienambulanz Hartard
RECRUITING

Munich, Bavaria, 80809, Germany
Cardio D&R Košice
RECRUITING

Košice, 040 22, Slovakia
Cedar Health Research
RECRUITING

Dallas, Texas, 75251, United States
CenExcel Rocky Mountain Clinical Research, LLC
RECRUITING

Englewood, Colorado, 80113, United States
CenExel CBH Health
RECRUITING

Gaithersburg, Maryland, 20877, United States
CenExel FCR - ForCare Clinical Research
RECRUITING

Tampa, Florida, 33613, United States
CenExel HRI - Hassman Research Institute
RECRUITING

Marlton, New Jersey, 08053, United States
CenExel iResearch, LLC
RECRUITING

Savannah, Georgia, 31405, United States
Centricity Research Etobicoke Endocrinology
RECRUITING

Etobicoke, Ontario, M9R 4E1, Canada
Centricity Research Mirabel Multispecialty (Centricity Research)
RECRUITING

Mirabel, Quebec, J7J 2K8, Canada
Centru Medical "GRANDMED"
RECRUITING

Oradea, 410032, Romania
Centrul Medical Mediab - Mediab Srl
RECRUITING

Târgu Mureş, 540142, Romania
Centrum Badan Klinicznych PI-House Sp. z o.o.
RECRUITING

Gdansk, 80-546, Poland
Centrum Medyczne Pratia Gdynia
RECRUITING

Gdynia, 81-338, Poland
Centrum Medyczne Pratia Katowice
RECRUITING

Katowice, 40-081, Poland
Centrum Terapii Współczesnej J.M. Jasnorzewska Spółka Komandytowo-Akcyjna
RECRUITING

Lodz, 90-338, Poland
Centrum medyczne Pratia Bydgoszcz
RECRUITING

Bydgoszcz, 85-796, Poland
Civia Health Goodlettsville
RECRUITING

Goodlettsville, Tennessee, 37072, United States
Civia Health Independence
NOT_YET_RECRUITING

Independence, Missouri, 64055, United States
Civia Health Memphis
NOT_YET_RECRUITING

Memphis, Tennessee, 38117, United States
Civia Health Nashville
RECRUITING

La Vergne, Tennessee, 37086, United States
Civia Health St. Louis
NOT_YET_RECRUITING

Creve Coeur, Missouri, 63141, United States
Civia Health Sunderland
RECRUITING

Hendon, CITY of Sunderland, SR1 1PB, United Kingdom
Civia Health_Boots Birmingham
RECRUITING

Birmingham, B4 7TA, United Kingdom
Civia Health_Boots Nottingham
RECRUITING

Nottingham, NG1 3QS,, United Kingdom
Clifton Medical Centre
RECRUITING

Rotherham, S651DA, United Kingdom
Clinical Innovations, Inc dba CITrials
RECRUITING

Riverside, California, 92506, United States
Clinical Research Professionals
RECRUITING

Chesterfield, Missouri, 63005, United States
Collaborative Neuroscience Research, LLC
RECRUITING

Garden Grove, California, 92845, United States
DIABEDA s.r.o.
RECRUITING

Bratislava, Bratislava, Slovakia
Dallas Clinical Research Center (Pillar Clinical Research)
RECRUITING

Richardson, Texas, 75080, United States
DelRicht Research @ Springer Wellness and Restorative Health
RECRUITING

Atlanta, Georgia, 30329, United States
Diabetes Studienzentrum Wilhelmsburg
RECRUITING

Hamburg, 21109, Germany
Diabetespraxis Dr. Braun
RECRUITING

Berlin, 13187, Germany
Diabeteszentrum Hamburg-West
RECRUITING

Hamburg, 22607, Germany
Diagnostic Consultative Center Aleksandrovska
RECRUITING

Sofia, 1431, Bulgaria
ETG Siedlce
RECRUITING

Siedlce, 08-110, Poland
Ecg Médica S.L.
RECRUITING

Valencia, 46015, Spain
Edumed s.r.o.
RECRUITING

Náchod, 54701, Czechia
Ekamed Sp. z o. o.
RECRUITING

Lublin, 20-718, Poland
Etg Warszawa
RECRUITING

Warsaw, 02-677, Poland
Eximia EquiHealth Research
RECRUITING

Durham, North Carolina, 27704, United States
Fakultní nemocnice Královské Vinohrady
RECRUITING

Prague, 100 34, Czechia
Forum Austin (Civia Health)
RECRUITING

Austin, Texas, 78758, United States
Forum Health Cary
RECRUITING

Cary, North Carolina, 27511, United States
Fundatia Dr Victor Babes
RECRUITING

Bucharest, 30303, Romania
Future Medical Research (Civia Health)
RECRUITING

Longwood, Florida, 32750, United States
FutureMeds Berlin
RECRUITING

Berlin, 10629, Germany
FutureMeds Birmingham
RECRUITING

Birmingham, B21 9RY, United Kingdom
FutureMeds Frankfurt/Offenbach
RECRUITING

Offenbach, 63065, Germany
FutureMeds Gdynia
RECRUITING

Gdynia, 81-384, Poland
FutureMeds Glasgow McCafferty House
RECRUITING

Glasgow, Scotland, G20 7BE, United Kingdom
FutureMeds Krakow
RECRUITING

Krakow, 31-501, Poland
FutureMeds Liverpool
RECRUITING

Bromborough, CH62 6EE, United Kingdom
FutureMeds Lodz
RECRUITING

Lodz, 91-393, Poland
FutureMeds London
RECRUITING

London, NW10 2PB, United Kingdom
FutureMeds Newcastle upon Tyne
RECRUITING

Newcastle upon Tyne, NE6 1SG, United Kingdom
FutureMeds Olsztyn
RECRUITING

Olsztyn, 10-165, Poland
FutureMeds Teesside
RECRUITING

Stockton-on-Tees, TS19 8PE, United Kingdom
FutureMeds Warszawa Centrum
RECRUITING

Warsaw, 00-215, Poland
FutureMeds Warszawa Targowek
RECRUITING

Warsaw, 03-291, Poland
FutureMeds Wroclaw
RECRUITING

Wroclaw, 53-673, Poland
Futuremeds S.R.L., Brasov
RECRUITING

Brasov, 500388, Romania
Futuremeds S.R.L., Craiova
RECRUITING

Criaova, 200115, Romania
Futuremeds S.R.L., Galati
RECRUITING

Galati, Romania
Futuremeds Spain Cadiz
RECRUITING

Chiclana de la Frontera, 11139, Spain
Futuremeds Spain Madrid
RECRUITING

Madrid, 28003, Spain
Futuremeds Spain Sevilla
RECRUITING

Seville, 41012, Spain
GLRI El Paso Research
RECRUITING

El Paso, Texas, 79936, United States
Gemeinschaftspraxis Dres. H.Kittner und K.Hartig
RECRUITING

Naunhof, 04683, Germany
Headlands Research
RECRUITING

Scottsdale, Arizona, 85260, United States
Hightech Medical Services S.R.L (Centrul pentru Studiul Metabolismului)
RECRUITING

Bucharest, 011053, Romania
Hospital Universitario Virgen de la Victoria
RECRUITING

Málaga, Málaga, 29010, Spain
Hospital Virgen del Camino
RECRUITING

Sanlúcar de Barrameda, 11540, Spain
Hospital Vithas Sevilla
RECRUITING

Castilleja de la Cuesta, 41950, Spain
IRMED
RECRUITING

Piotrkow Trybunalski, 97-300, Poland
Institutul Clinic Fundeni
RECRUITING

Bucharest, 022328, Romania
Institutul National de Endocrinologie "C.I. Parhon"
RECRUITING

Bucharest, 011863, Romania
Instytut Diabetologii.sp.z.o.o.
RECRUITING

Warsaw, 02-117, Poland
JAL s.r.o.
RECRUITING

Trnava, 91701, Slovakia
Kiltearn Medical Centre
RECRUITING

Nantwich, CW5 5NX, United Kingdom
Klinische Forschung Berlin-Mitte GmbH
RECRUITING

Berlin, 10117, Germany
Klinische Forschung Dresden GmbH / Pratia
RECRUITING

Dresden, 01069, Germany
Klinische Forschung Hamburg GmbH / Pratia
RECRUITING

Hamburg, 20253, Germany
Klinische Forschung Karlsruhe GmbH
RECRUITING

Karlsruhe, 76137, Germany
LMC Diabetes & Endocrinology - Bayview (Centricity Research Toronto LMC Multispecialty)
RECRUITING

Toronto, Ontario, M4G 3E8, Canada
MC Nevromedics Ltd.
RECRUITING

Veliko Tarnovo, 5005, Bulgaria
MEDI-DIA s.r.o
RECRUITING

Sabinov, 083 01, Slovakia
MHAT Botevgrad
RECRUITING

Botevgrad, 2140, Bulgaria
MHAT Sveta Karidad EAD
RECRUITING

Plovdiv, 4004, Bulgaria
Medical Center - Clinic Nova EOOD
RECRUITING

Varna, 9000, Bulgaria
Medical Center 4Life EOOD
RECRUITING

Burgas, 8018, Bulgaria
Medical Center Berbatov
RECRUITING

Yambol, 8600, Bulgaria
Medical Center Futuremeds EOOD
RECRUITING

Plovdiv, 4000, Bulgaria
Medical Center Hera EOOD
RECRUITING

Sofia, 1510, Bulgaria
Medical Center New Polyclinic Gabrovo Ltd.
RECRUITING

Gabrovo, 5300, Bulgaria
Medical Center Zdrave 1
RECRUITING

Kozloduy, 3320, Bulgaria
Medical Centre Pratia Clinic EOOD
RECRUITING

Varna, 9020, Bulgaria
Medical group Kosice s.r.o.
RECRUITING

Košice, 04001, Slovakia
Medicome Sp. z o.o. Oświęcimskie Centrum Badań Klinicznych
RECRUITING

Oświęcim, 32-600, Poland
Medislim GmbH
RECRUITING

Weinheim, 69469, Germany
Medispektrum s.r.o.
RECRUITING

Bratislava, 85101, Slovakia
Medivasa s.r.o
RECRUITING

Žilina, 010 01, Slovakia
Medizentrum Essen Borbeck
RECRUITING

Essen, 45355, Germany
Metabolica Sp. z o.o., NZOZ METABOLICA Ośrodek Badań Klinicznych
RECRUITING

Tarnów, 33-100, Poland
Minimed S.R.L.
RECRUITING

Bacau, 600237, Romania
Multiprofile Hospital for Active Treatment Dobrich AD (MHAT Dobrich AD)
RECRUITING

Dobrich, 9300, Bulgaria
NZOZ Centrum Medyczne KERmed
RECRUITING

Bydgoszcz, 85-231, Poland
Nemocnice Jihlava
RECRUITING

Jihlava, 58601, Czechia
Nuevas Tecnologías en Diabetes y Endocrinología S.L.
RECRUITING

Seville, 41003, Spain
Oviedo Medical Research
RECRUITING

Oviedo, Florida, 32765, United States
Pantheon Clinical Research
RECRUITING

Bountiful, Utah, 84010, United States
Panthera Biopartners Limited - Enfield
RECRUITING

Enfield, EN3 4GS, United Kingdom
Panthera Biopartners Limited - Glasgow
RECRUITING

Glasgow, G51 4TY, United Kingdom
Panthera Biopartners Limited - Preston
RECRUITING

Preston, PR2 9QB, United Kingdom
Panthera Biopartners Limited - Rochdale
RECRUITING

Rochdale, OL11 4AU, United Kingdom
Panthera Biopartners Limited - Sheffield
RECRUITING

Sheffield, S2 5FX, United Kingdom
Panthera Biopartners Limited - York
RECRUITING

York, YO24 4LJ, United Kingdom
Peninsula Headlands LLC
RECRUITING

Rolling Hills, California, 90274, United States
Poliklinika Váš Lekár
RECRUITING

Bratislava, 82109, Slovakia
Praktyka Lekarska Ewa Krzyzagorska
RECRUITING

Poznan, 61-655, Poland
Pratia Brno,s.r.o
RECRUITING

Brno, 60200, Czechia
Pratia Chojnice
RECRUITING

Chojnice, 89-600, Poland
Pratia Pardubice
RECRUITING

Pardubice, 53002, Czechia
Praxis Reinfeld Mitte
RECRUITING

Holstein, 23858, Germany
Praxis am Markt - Dr. Bernd Becker
RECRUITING

Essen, 45355, Germany
Prevencia - 2000 - Medical Center for Prehospital Medical Care OOD
RECRUITING

Stara Zagora, 6000, Bulgaria
Primary Care Research (Civia Health)
RECRUITING

Papillion, Nebraska, 68046, United States
Quality Clinical Research Inc
RECRUITING

Omaha, Nebraska, 68114, United States
ResTrial s.r.o.
RECRUITING

Prague, 18100, Czechia
Research Centers of America
RECRUITING

Hollywood, Florida, 33024, United States
Santa Familia PTG Lodz
RECRUITING

Lodz, Łódź Voivodeship, 90-302, Poland
Sc Gensan Srl/Policlinica Astra
RECRUITING

Sibiu, 550371, Romania
Southmead Hospital
RECRUITING

Bristol, BS10 5NB, United Kingdom
Studienzentrum FMZ Radowsky
RECRUITING

Leipzig, Saxony, 4179, Germany
Summit Headlands LLC
RECRUITING

Portland, Oregon, 97210, United States
Synexus Glasgow Clinical Research Centre
RECRUITING

Bellshill, ML4 3NJ, United Kingdom
Synexus Manchester Clinical Research Centre
RECRUITING

Manchester, M15 6SE, United Kingdom
Synexus Midlands Clinical Research Centre
RECRUITING

Birmingham, B15 2SQ, United Kingdom
Synexus Polska Sp z o.o.
RECRUITING

Gdansk, 80-382, Poland
Synexus Polska Sp. Z O.O. Oddzial W Katowicach
RECRUITING

Katowice, 40-040, Poland
Synexus Polska Sp. z o.o. Oddzial w Gdyni
RECRUITING

Gdynia, 81-537, Poland
Synexus Polska Sp. z o.o., Oddzial w Czestochowie
RECRUITING

Częstochowa, 42-202, Poland
Synexus Polska Sp. z o.o., Oddzial w Lodzi
RECRUITING

Lodz, 90-127, Poland
Synexus Polska Sp. z o.o., Oddzial w Warszawie
RECRUITING

Warsaw, 02-672, Poland
Synexus Polska Sp. z o.o., Oddział w Poznaniu
RECRUITING

Poznan, 60-702, Poland
Synexus Polska Sp. z o.o., Oddział we Wrocławiu
RECRUITING

Wroclaw, 50-381, Poland
Synexus/Trialmed Prague
RECRUITING

Prague, 120 00, Czechia
TMA Headlands LLC
RECRUITING

Wilmington, North Carolina, 28403, United States
Tatratrial s.r.o.
RECRUITING

Rožňava, 048 01, Slovakia
The Wharton Medical Clinic Clinical Trials Inc
RECRUITING

Hamilton, Ontario, L8L 5G8, Canada
Trialmed CRS
RECRUITING

Piotrkow Trybunalski, 97-300, Poland
Tribe Clinical Research, LLC
RECRUITING

Greenville, South Carolina, 29607, United States
Tribe Clinical Research, LLC
RECRUITING

Spartanburg, South Carolina, 29301, United States
Upgrade Performance Institute
RECRUITING

Elkhorn, Nebraska, 68022, United States
Velocity Clinical Research Germany
RECRUITING

Berlin, 10787, Germany
Zdrowie Osteo Medic sc L i A Racewicz, A i J Supronik
RECRUITING

Bialystok, 15-351, Poland
Zentrum für klinische Forschung
RECRUITING

Cologne, 51069, Germany
Zentrum für klinische Forschung Allgäu-Oberschwaben
RECRUITING

Wangen, 88239, Germany
Zentrum für klinische Studien Bad Homburg
RECRUITING

Bad Homburg, 61348, Germany