NON-SMALL CELL LUNG CARCINOMA

This study looked at whether adding metformin (a common diabetes medicine) to standard chemotherapy and radiation therapy helps people with stage III non-small cell lung cancer live longer without the cancer growing. About 170 people took part. The goal was to see if the combinat…

This study tested whether adding vibostolimab to pembrolizumab (Keytruda) helps people with advanced PD-L1 positive non-small cell lung cancer live longer or keep cancer from growing, compared to pembrolizumab alone. Over 1,200 participants received either the combination or the …

This phase 2 trial tested the immunotherapy drug pembrolizumab given before and after surgery in 35 people with early-stage non-small cell lung cancer. The goal was to see if this approach is safe and helps the immune system attack cancer cells. The study found that most patients…

This study tested a new immunotherapy drug, cemiplimab, against standard chemotherapy in 712 people with advanced non-small cell lung cancer that has a specific marker (PD-L1). The goal was to see if cemiplimab helps people live longer or keeps the cancer from growing longer than…

This study looked at how well the drug lorlatinib works for people with advanced non-small cell lung cancer that has a specific gene change (ALK). All 73 participants had already tried other treatments and their cancer was no longer controlled. The study found that lorlatinib hel…

This study tested a targeted drug called capmatinib in 50 Indian adults with advanced non-small cell lung cancer that has a specific genetic change (MET exon 14 skipping mutation). The goal was to check how safe the drug is and how well it shrinks tumors. Participants could be ne…

This early-phase study tested a system that measures how much laser light reaches tumors during photodynamic therapy (PDT) in people with mesothelioma, non-small cell lung cancer, or other cancers that spread to the lining of the lungs. Nine participants received a light-activate…

This study looked at whether a simple blood test can detect genetic changes from lung cancer tumors. Researchers tested 200 patients with non-small cell or small cell lung cancer to see if the test could track how the disease changes over time. The goal was to find a less invasiv…

This study followed 46 people with a type of lung cancer that hadn't caused symptoms yet. Doctors chose either to give radiation right away or wait and watch. The goal was to see what doctors usually do and how patients felt over time. No new treatment was tested—just current pra…