NON-SMALL CELL LUNG CARCINOMA

This study tests a vaccine made from lung cancer cells, combined with an immune-boosting drug (N-803), in people who have had surgery for non-small cell lung cancer (NSCLC) and have no signs of cancer left. The goal is to see if the vaccine can train the immune system to recogniz…

This early-phase study tested a vaccine (p53MVA) plus the drug pembrolizumab in 11 adults with advanced solid tumors that had stopped responding to other treatments. The goal was to see if the combination is safe and can boost the immune system to attack cancer cells. Participant…

This study tests a combination of two drugs, trastuzumab deruxtecan and pembrolizumab, in adults with advanced breast or non-small cell lung cancer that has spread. The goal is to find the safest dose and see how well the combo shrinks tumors. About 115 participants will receive …

This program gives patients with serious non-small cell lung cancer access to the drug capmatinib when no other treatments are available and they cannot join a clinical trial. It is not a study to test the drug, but a way for doctors to request it for individual patients who migh…

This study looks at whether adding high-dose vitamin C (ascorbate) to the usual treatment of radiation and chemotherapy can help people with non-small cell lung cancer. About 43 participants will receive the vitamin C alongside their standard therapy. The goal is to see if this c…

This study tests a new drug called JDQ443, given alone or with other treatments, for people with advanced solid tumors that have a specific change in the KRAS gene (G12C). The goal is to find safe doses and see if the drug can shrink tumors. About 74 adults with lung or colorecta…

This study tests an experimental drug called AZD2936 in people with advanced or metastatic non-small cell lung cancer (NSCLC). The drug is designed to help the immune system fight cancer by blocking two targets (TIGIT and PD-1). The main goals are to check safety and see if the d…

This study looks at whether adding acupuncture to standard immunotherapy and chemotherapy can help people with advanced non-small cell lung cancer. About 60 participants will receive either real or sham acupuncture alongside their first four cycles of treatment. The goal is to se…

This study tests an online program designed to improve social well-being and emotional support for women with non-small cell lung cancer. About 70 women currently receiving treatment will use mindfulness and compassion techniques to help manage distress. The goal is to see if the…

This study collects blood samples from 102 people with non-small cell lung cancer, colorectal cancer, or pancreatic cancer to track genetic changes in their tumors over time. Participants receive standard treatments, and researchers analyze DNA from the blood to see how it relate…