New targeted pill shows promise for rare lung cancer mutation

NCT ID NCT05110196

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a drug called capmatinib in 50 Indian adults with advanced non-small cell lung cancer that has a specific genetic change (MET exon 14 skipping mutation). The goal was to see how safe the drug is and how well it shrinks tumors. Participants took capmatinib pills, and researchers monitored side effects and cancer response.

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Conditions

The condition(s) this trial relates to.

bronchial neoplasm carcinoma lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Novartis Investigative Site

    Gujarat, Gujarat, 380016, India

  • Novartis Investigative Site

    Mangalore, Karnataka, 575002, India

  • Novartis Investigative Site

    Thalassery, Kerala, 670103, India

  • Novartis Investigative Site

    Trivandrum, Kerala, 695 011, India

  • Novartis Investigative Site

    Bhopal, Madhya Pradesh, 462001, India

  • Novartis Investigative Site

    Mumbai, Maharashtra, 400 012, India

  • Novartis Investigative Site

    Mumbai, Maharashtra, 400056, India

  • Novartis Investigative Site

    Nagpur, Maharashtra, 441108, India

  • Novartis Investigative Site

    Pune, Maharashtra, 411040, India

  • Novartis Investigative Site

    New Delhi, National Capital Territory of Delhi, 110029, India

  • Novartis Investigative Site

    Bhubaneswar, Odisha, 751007, India

  • Novartis Investigative Site

    Hyderabad, Telangana, 500004, India

  • Novartis Investigative Site

    Varanasi, Uttar Pradesh, 221005, India

  • Novartis Investigative Site

    Kolkata, West Bengal, 700 020, India

  • Novartis Investigative Site

    Puducherry, 605006, India