Laser and Light-Sensitive drug shrink lung tumors in early trial
NCT ID NCT03735095
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial tested a treatment called photodynamic therapy for people with advanced lung cancer that blocks airways. Patients received a light-sensitive drug followed by a laser to activate it inside the tumor. The goal was to see if the treatment is safe and can shrink tumors to ease symptoms. Nineteen adults with lung cancer took part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Porfimer sodium (a light-sensitive drug)
- What this could lead to
- If successful, this approach could offer a new way to shrink airway-blocking tumors and improve breathing in people with advanced lung cancer.
- What could go wrong
- This is an early-phase trial with only 19 participants, so results may not apply to everyone. The treatment involves a drug that makes skin and eyes sensitive to light, and there is a risk of serious side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for LOCALLY ADVANCED LUNG CARCINOMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Roswell Park Cancer Institute
Buffalo, New York, 14263, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new drug shield nerves from Chemotherapy's side effects?
- Could a common heartburn drug shield lung cancer patients from radiation side effects?
- Can a targeted pill keep lung cancer from returning?
- Can a Tumor's DNA guide better cancer care for kids?
- Can a new PET tracer reveal a key cancer target?
- Can a smart drug home in on Hard-to-Treat cancers?