NARCOLEPSY TYPE 1
Clinical trials for NARCOLEPSY TYPE 1 explained in plain language.
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New pill shows promise for keeping sleep disorders in check over the long haul
Disease control Recruiting nowThis study looks at the long-term safety and how well ALKS 2680 works for people with narcolepsy type 1, type 2, or idiopathic hypersomnia. About 256 adults who finished a previous ALKS 2680 study will take the tablet and be monitored for side effects and improvements in daytime …
Matched conditions: NARCOLEPSY TYPE 1
Phase: PHASE2, PHASE3 • Sponsor: Alkermes, Inc. • Aim: Disease control
Last updated May 17, 2026 08:05 UTC
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Narcolepsy drug TAK-861 tested for long-term safety in 500 patients
Disease control Recruiting nowThis study looks at the long-term safety of the drug TAK-861 in 500 people with type 1 narcolepsy who have already taken it in a previous study. Researchers will track side effects and measure how well patients can stay awake. The goal is to see if the drug remains safe and toler…
Matched conditions: NARCOLEPSY TYPE 1
Phase: PHASE2, PHASE3 • Sponsor: Takeda • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New pill aims to keep narcolepsy patients awake and safe from sudden falls
Symptom relief Recruiting nowThis study tests an experimental tablet called ALKS 2680 in 150 adults with narcolepsy type 1, a condition causing severe daytime sleepiness and sudden muscle weakness (cataplexy). Participants receive either the drug or a placebo for 12 weeks. The goal is to see if the drug help…
Matched conditions: NARCOLEPSY TYPE 1
Phase: PHASE3 • Sponsor: Alkermes, Inc. • Aim: Symptom relief
Last updated May 17, 2026 07:59 UTC
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New orexin mimic aims to wake up sleepy patients
Symptom relief Recruiting nowThis study tests a new drug called ORX750 (cleminorexton) that mimics a natural brain protein (orexin) to help people stay awake. It includes 248 adults with narcolepsy type 1, type 2, or idiopathic hypersomnia. The main goals are to check safety and see if the drug reduces dayti…
Matched conditions: NARCOLEPSY TYPE 1
Phase: PHASE2 • Sponsor: Centessa Pharmaceuticals (UK) Limited • Aim: Symptom relief
Last updated May 17, 2026 07:57 UTC
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New sleep drug ORX750 tested for long-term safety in narcolepsy and hypersomnia patients
Symptom relief Recruiting nowThis study looks at the long-term safety and effectiveness of a drug called ORX750 in people with narcolepsy (types 1 and 2) or idiopathic hypersomnia who have already completed a previous ORX750 study. About 90 participants will take the drug and be monitored for side effects an…
Matched conditions: NARCOLEPSY TYPE 1
Phase: PHASE2 • Sponsor: Centessa Pharmaceuticals (UK) Limited • Aim: Symptom relief
Last updated May 12, 2026 13:43 UTC
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Could pain predict Parkinson's? new study investigates
Knowledge-focused Recruiting nowThis study looks at whether people with idiopathic REM sleep behavior disorder (iRBD) experience more pain than those with narcolepsy and RBD. iRBD is a strong early sign of Parkinson's disease, but pain in these patients has not been studied before. Researchers will compare pain…
Matched conditions: NARCOLEPSY TYPE 1
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated May 17, 2026 08:05 UTC
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Gut leaks linked to narcolepsy? new study investigates
Knowledge-focused Recruiting nowThis study looks at whether gut bacteria and bacterial leakage into the blood and spinal fluid play a role in type 1 narcolepsy, a rare sleep disorder. Researchers will compare 120 people with and without narcolepsy to understand how gut health might trigger the immune system to …
Matched conditions: NARCOLEPSY TYPE 1
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 08:04 UTC
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Spain launches first nationwide narcolepsy census
Knowledge-focused Recruiting nowThis study aims to find out how many people in Spain have been diagnosed with narcolepsy type 1 or type 2, and how many new cases are diagnosed each year. Researchers will review medical records from hospitals across Spain to count patients and understand patterns. The study does…
Matched conditions: NARCOLEPSY TYPE 1
Sponsor: Takeda • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC