New pill aims to keep narcolepsy patients awake and safe from sudden falls

NCT ID NCT07455383

First seen Mar 11, 2026 · Last updated May 15, 2026 · Updated 12 times

Summary

This study tests an experimental tablet called ALKS 2680 in 150 adults with narcolepsy type 1, a condition causing severe daytime sleepiness and sudden muscle weakness (cataplexy). Participants receive either the drug or a placebo for 12 weeks. The goal is to see if the drug helps people stay awake longer and reduces cataplexy episodes. This is a phase 3 trial, meaning it is one of the final steps before possible approval.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alkermes Investigational Site

    RECRUITING

    Brandon, Florida, 33511, United States

  • Alkermes Investigational Site

    RECRUITING

    Macon, Georgia, 31210, United States

  • Alkermes Investigational Site

    RECRUITING

    Lansing, Michigan, 48911, United States

  • Alkermes Investigational Site

    RECRUITING

    St Louis, Missouri, 63123, United States

  • Alkermes Investigational Site

    RECRUITING

    Cincinnati, Ohio, 45245, United States

  • Alkermes Investigational Site

    RECRUITING

    Wyomissing, Pennsylvania, 19610, United States

  • Alkermes Investigational Site

    RECRUITING

    Columbia, South Carolina, 29201, United States

  • Alkermes Investigational Site

    RECRUITING

    Austin, Texas, 78731, United States

  • Alkermes Investigational Site

    RECRUITING

    Sugar Land, Texas, 77478, United States

Conditions

Explore the condition pages connected to this study.