MYOPIA

This trial evaluates Paragon CRT contact lenses with a 5mm optic zone diameter, worn overnight to temporarily reshape the cornea and correct myopia and astigmatism. Participants aged 6 to 35 will wear the lenses daily for a short period, and their comfort and visual performance w…

This trial tests whether dual-focus contact lenses, which have special rings to slow eye growth, can reduce the progression of myopia (nearsightedness) in young adults aged 18 to 30. Participants will wear either these lenses or standard single-vision lenses for 24 months. The st…

This trial studies children aged 8 to 16 who have used repeated low-level red light (RLRL) therapy for one year to control nearsightedness (myopia). Participants are randomly assigned to either continue the therapy, stop it completely, or gradually reduce it. The goal is to see h…

This study tests whether oral dietary supplements can improve the health of the back of the eye in children with nearsightedness (myopia). About 156 children aged 8-13 will take either a supplement or a placebo for a period, and researchers will measure changes in the thickness a…

This trial tests whether a device called OcuLign, which automatically adjusts for eye rotation during SMILE surgery, corrects astigmatism better than the standard manual marking method. Adults aged 18 to 40 with stable myopia and astigmatism will have one eye treated with each me…

This study tests whether special glasses called Kubota Glass can temporarily change the length of the eye, which is key to controlling nearsightedness (myopia). Participants aged 8 to 24 with mild to moderate myopia will try five different lens settings in a randomized, double-ma…

This study compares two types of spectacle lenses designed to slow the progression of myopia (nearsightedness) in children aged 6 to 10. The goal is to see if the new test lenses are as comfortable and easy to adapt to as the control lenses during the first two weeks of wear. Chi…

This study compares two types of special glasses (DIMS and DOT) to control nearsightedness in children aged 6 to 12 who also have intermittent exotropia (a type of eye misalignment). Researchers want to see which lens works better and whether the glasses affect eye coordination. …

This study tests two types of daily disposable contact lenses designed to slow the progression of myopia (nearsightedness) in children aged 7 to 12. Over two years, 126 Hong Kong Chinese children will wear either a special lens or a standard single-vision lens, with their eyes me…

This study tests two types of modified spectacle lenses designed to slow the progression of myopia (nearsightedness) in children aged 6 to 13. Over one year, researchers will measure changes in the back of the eye (choroid), eye length, and prescription strength. The goal is to s…

This study tests whether special research glasses can reduce the difference in prescription between the two eyes in children aged 6 to 13 with myopic anisometropia (when one eye is much more nearsighted than the other). Twenty children will wear the study glasses and have their e…

This study tests if low-intensity red light therapy can slow or stop the worsening of high and extreme myopia (severe nearsightedness) in adults aged 18 to 45. The treatment has shown promise in children, but its effects in adults are unknown. The goal is to prevent vision loss a…

This trial tests a red light device that uses LED light to control myopia (nearsightedness) in children aged 6 to 18. About 206 kids will use either the real device or a fake one to see if the red light can slow eye growth and reduce the need for stronger glasses. The study focus…

This study tests if using a special LED red light device twice a day, along with glasses that have defocus lenses, can slow the progression of nearsightedness (myopia) in children aged 6 to 14. About 364 kids will be randomly assigned to different groups to find the best treatmen…

This study tests whether repeated low-intensity red light can treat myopia (nearsightedness) in adults aged 18 to 35. Thirty participants will use a red light device 1 to 3 times daily. Researchers will measure changes in eye length and prescription strength to see if the treatme…

This study tests whether low-dose atropine eye drops (0.05%) can slow the progression of myopia (nearsightedness) in children. Forty-five kids with worsening myopia will receive one drop of atropine in one eye and a placebo drop in the other eye every night for 24 months. The mai…

This study will test a new, non-invasive eye scanner called wide field OCTA in 200 people with various eye diseases, including age-related macular degeneration, diabetic retinopathy, and dry eye. The goal is to see if this device can provide better images of blood vessels in the …

This study tests a new device designed to measure nearsightedness and astigmatism. Researchers will compare its accuracy to standard tools used by eye doctors. Thirty adults aged 18-39 who wear glasses will participate. The goal is to see if the new device works as well as curren…

This study checks if a Turkish version of the DDIVAT digital vision test gives the same results as the standard Snellen eye chart. About 200 Turkish-speaking adults, with or without glasses, will take both tests. No drugs or procedures are involved, and there are no risks.

This trial tests whether special glasses with defocus lenses, aided by artificial intelligence, can prevent myopia in children aged 3 to 6 who are at high risk. The glasses are worn for at least 10 hours a day, and a smartwatch reminds kids to spend time outdoors. The study measu…

This trial tests whether combining a daily 18-minute virtual reality training session with low-dose atropine eye drops can slow the worsening of nearsightedness in children aged 6 to 12. Participants will also wear special glasses that provide defocus to the peripheral vision. Th…

This study tests whether special glasses lenses can prevent nearsightedness (myopia) in children aged 6 to 8 who are not yet nearsighted. About 255 children will wear either a new type of lens or a standard lens for at least 8 hours a day for one year. Researchers will check thei…

This study tests whether pressing tiny pellets on ear points can delay or prevent nearsightedness (myopia) in children aged 4 to 14 who are at high risk. It compares ear acupressure, low-dose atropine eye drops, and a combination of both. The goal is to find a safe, non-drug way …

This study tests a 24-week school program to prevent myopia, obesity, and mental health problems in children aged 8-11. The program includes animated videos, family activities, and health lessons. Researchers will compare these kids to those receiving standard health education, t…

This study tests whether sending regular health education messages about eye care to parents via WeChat can improve how children use their eyes and slow or prevent nearsightedness. About 1,330 third-grade students in China will take part, with their guardians receiving the messag…

This study tests whether replacing some regular gym classes with specialized physical education courses can prevent common health issues like nearsightedness, overweight, anxiety, and depression in junior high students. Two hundred students will be randomly assigned to either the…

This study explores whether a type of visual training called perceptual learning can improve uncorrected vision in children aged 6 to 10 with low myopia (mild nearsightedness). Thirty children will be randomly assigned to either a training group that uses a digital Vision Trainin…

This trial compares two types of laser eye surgery—SMILE and ray tracing-guided LASIK—in people with nearsightedness and astigmatism. Each participant will receive one technique in one eye and the other in the other eye, allowing a direct comparison. The goal is to see which meth…

This study tests a new excimer laser for LASIK surgery to correct mild nearsightedness (up to -1.00 diopter) with or without astigmatism. About 32 adults aged 22 and older will receive the treatment in one or both eyes. The goal is to see if the laser safely and accurately improv…

This study tests a new daily disposable contact lens called ST-1 against an existing lens, Miru 1day UpSide, in 63 people with nearsightedness. Participants will wear the lenses daily for 3 months and have their vision and eye comfort checked regularly. The goal is to see if the …

This study compares how various myopia control methods—like special glasses, contact lenses, eye drops, and light therapy—affect eye strain in children and adolescents aged 6 to 18. Researchers will survey 600 participants to see which approaches cause the least visual fatigue. T…

This study will use a special imaging device (AS-OCT) to measure the thickness of the cornea's outer layer in 360 adults with nearsightedness, farsightedness, astigmatism, or normal vision. The goal is to see if different vision problems have unique thickness patterns. Participan…

This study will measure how eye pressure changes after common laser vision correction surgeries like PRK, LASIK, and femtosecond laser. Researchers will compare two measurement methods—Corvis CT and the standard applanation tonometer—in 50 people aged 19 to 35 with mild to modera…

This study will measure how pupil size and eye shape affect visual quality in 300 people with normal eyes or after refractive surgery. Researchers will use questionnaires and special instruments to track symptoms and eye measurements. The goal is to better understand what influen…

This study will compare 40 nearsighted children to 40 children with normal vision, all aged 8 to 13. Researchers will measure how much oxygen the retina uses and look at blood flow and eye structure. The goal is to learn whether low oxygen plays a role in causing myopia. No treat…

This study looks at how the length of the eye and the amount of nearsightedness or farsightedness relate to the health of the optic nerve and surrounding layers. Researchers will use a special camera (OCT) to take detailed images of the eye in 266 adults. The goal is to better un…

This study will analyze corneal tissue that is normally thrown away during a common myopia surgery called CLEAR (or SMILE). Researchers will test the tissue's strength and structure to learn more about how the cornea behaves. The goal is to improve future eye surgeries by underst…