MYELODYSPLASTIC SYNDROMES

This study is testing an investigational drug called TAK-226 to see if it can help Japanese adults with a lower-risk bone marrow disorder become less dependent on regular blood transfusions. The main goal is to see if participants can go at least 8 weeks without needing a transfu…

This study is testing whether a drug called interferon-α can help prevent cancer from coming back in patients with high-risk forms of leukemia or myelodysplastic syndrome (MDS) who have just received a stem cell transplant. It will involve 100 patients aged 12-65 who have a speci…

This study is testing a new combination of two drugs, pacritinib and azacitidine, for people with a type of blood and bone marrow cancer called myelodysplastic syndrome (MDS). The first part of the study will find the safest dose. The second part will see if this dose helps contr…

This early-stage study is testing whether adding an oral drug called momelotinib to a standard injected therapy (azacitidine) is safe and effective for people with certain rare, overlapping blood cancers. The goal is to better control the disease, reduce symptoms like an enlarged…

This study aims to see if it's safe and possible to stop a key anti-rejection medication (tacrolimus) much earlier than usual after a bone marrow transplant. It will involve 50 adults with various blood cancers who receive a transplant from a matched donor. The goal is to reduce …

This study is testing whether an online program combining mindfulness and music therapy can help patients feel better during and after a stem cell transplant. It aims to improve quality of life, reduce symptoms like pain and fatigue, and lower stress for 165 adults with blood can…

This study aims to understand how disorders in blood cell production are connected to various inflammatory and autoimmune diseases. Researchers will observe 5,000 adult patients who have these conditions, collecting their health information over time. The goal is to create a deta…