New hope for aggressive leukemia? drug combo targets tough genetic mutation

NCT ID NCT07511062

First seen Apr 07, 2026 · Last updated May 14, 2026 · Updated 5 times

Summary

This early-stage study tests a new drug called axatilimab added to standard chemotherapy for people with a specific, high-risk form of acute myeloid leukemia (AML) that has a TP53 mutation or deletion. The goal is to find the safest dose of axatilimab and see how well the combination works at clearing leukemia from the bone marrow. About 32 adults who have not been treated before or whose cancer has returned will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Northside Hospital, Inc.

    Atlanta, Georgia, 30342, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.