METASTATIC MELANOMA
Clinical trials for METASTATIC MELANOMA explained in plain language.
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New shot tested to boost cancer Drug's power against deadly skin cancer
Disease control TerminatedThis study tested if adding a new drug called CMP-001, injected directly into a tumor, could improve the effectiveness of the standard immunotherapy nivolumab for people with advanced melanoma that cannot be removed by surgery. It compared the combination treatment to nivolumab a…
Matched conditions: METASTATIC MELANOMA
Phase: PHASE2, PHASE3 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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First human test of Pfizer's new cancer drug begins
Disease control TerminatedThis early-stage study tested the safety and determined the right dosage of a new drug called PF-08046031 for adults with advanced melanoma and other solid tumors that have spread and have no other approved treatment options. The main goal was to identify side effects and see how…
Matched conditions: METASTATIC MELANOMA
Phase: PHASE1 • Sponsor: Pfizer • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Drug duo tested to fight cancer that spread to the brain
Disease control TerminatedThis study tested whether a combination of two drugs, pembrolizumab and lenvatinib, could shrink tumors in the brain for patients with melanoma or kidney cancer that had spread there. The trial was for patients whose cancer had worsened despite previous immunotherapy. The main go…
Matched conditions: METASTATIC MELANOMA
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Direct-to-Lymph node cancer treatment tested in early trial
Disease control TerminatedThis early-phase study tested the safety and best dose of an immunotherapy drug called STI-3031. The drug was delivered directly into the lymph vessels or nodes of a single limb using a special device, aiming to treat melanoma that had spread locally. The goal was to see if this …
Matched conditions: METASTATIC MELANOMA
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Doctors test engineered virus to attack deadly skin cancer
Disease control TerminatedThis early-phase study tested a genetically modified virus designed to kill melanoma cancer cells. The virus was injected directly into tumors and given intravenously to patients with advanced melanoma that had stopped responding to standard treatments. The main goals were to fin…
Matched conditions: METASTATIC MELANOMA
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Two-Pronged attack tested against brain tumors
Disease control TerminatedThis early-phase study tested a combination of two drugs, bintrafusp alfa and pimasertib, for patients with cancer that had spread to the brain (brain metastases). The goal was to find a safe dose and see if the combination could help control the brain tumors and help patients li…
Matched conditions: METASTATIC MELANOMA
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC