Experimental combo targets Hard-to-Treat melanoma

NCT ID NCT02706353

First seen Nov 21, 2025 · Last updated May 24, 2026 · Updated 26 times

Summary

This study looked at a new combination of two drugs for people with metastatic melanoma (cancer that has spread). The first part aimed to find the safest dose of an experimental drug (APX005M) when given with an approved immunotherapy (pembrolizumab). The second part checked if the combination helps control the cancer. The study was stopped early, but the goal was to improve treatment options for advanced melanoma.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.