Experimental combo therapy for brain metastases shows early safety signals

NCT ID NCT05341349

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage trial tested whether adding a device that creates electric fields (NovoTTF-200M) to standard radiation and immunotherapy is safe for people with melanoma that has spread to the brain. Only one person took part before the study was stopped early. The main goal was to check for serious side effects in the brain and skin.

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Conditions

The condition(s) this trial relates to.

brain cancer cancer of unknown primary site cutaneous melanoma melanoma metastatic malignant neoplasm in the brain metastatic melanoma mucosal melanoma Uveal Melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Emory University Hospital/Winship Cancer Institute

    Atlanta, Georgia, 30322, United States