MEDULLOBLASTOMA
Clinical trials for MEDULLOBLASTOMA explained in plain language.
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Scientists test Direct-to-Brain immune therapy in kids with aggressive tumors
Disease control CompletedThis early-phase study tested a personalized cell therapy for children and young adults with recurrent or hard-to-treat brain tumors. Doctors collected patients' own immune cells, engineered them in a lab to target a specific protein (EGFR) on the tumor, and then delivered these …
Matched conditions: MEDULLOBLASTOMA
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Study tests new radiation timing for Kids' brain cancer
Disease control CompletedThis completed international trial compared two different schedules of radiation therapy for children and young adults (ages 4-21) with standard-risk medulloblastoma, a type of brain tumor. All participants received the same chemotherapy, but were randomly assigned to receive rad…
Matched conditions: MEDULLOBLASTOMA
Phase: PHASE3 • Sponsor: Institut Curie • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Race for a better treatment: two chemo regimens battle childhood brain cancer
Disease control CompletedThis study aimed to find the best chemotherapy treatment for very young children (under 3 years old) with newly diagnosed, high-risk brain tumors. It directly compared two intense drug combinations, one with a drug called methotrexate and one without, to see which was more effect…
Matched conditions: MEDULLOBLASTOMA
Phase: PHASE3 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Scientists seek clues in fight against rare brain cancers
Knowledge-focused CompletedThis study aimed to gather information to better understand rare brain and spine tumors. Researchers collected health surveys and saliva samples from 326 adult participants who had been diagnosed with one of these rare cancers. The goal was to learn about risk factors, treatment …
Matched conditions: MEDULLOBLASTOMA
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists track Radiation's hidden toll on young brains
Knowledge-focused CompletedThis study aimed to understand the side effects of radiation therapy on children and young adults with brain tumors. Researchers followed 76 patients under age 21 for up to 5 years, collecting blood, urine, and MRI scans to measure biological changes. The goal was to learn how ra…
Matched conditions: MEDULLOBLASTOMA
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:18 UTC
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Scientists test DNA blueprint method to find better treatments for kids with tough cancers
Knowledge-focused CompletedThis study tested whether doctors could quickly analyze the genetic makeup of a child's tumor and use that information to choose a personalized treatment plan. It involved 186 children and young adults (up to age 21) whose cancers had returned or did not respond to standard treat…
Matched conditions: MEDULLOBLASTOMA
Phase: NA • Sponsor: Giselle Sholler • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:41 UTC