MEDULLOBLASTOMA

This study looked at two different chemotherapy treatments for children under 3 with certain aggressive brain tumors. The goal was to see if adding a drug called methotrexate to the standard chemo before a stem cell transplant helps more tumors shrink or disappear. The trial invo…

This study tested two different ways of giving radiation to children and teens (ages 4 to 21) with a standard-risk brain tumor called medulloblastoma. One method used smaller, more frequent doses (hyperfractionated), while the other used standard daily doses. The goal was to see …

This early-phase study tested a new treatment for children and young adults with brain tumors that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, which are modified in a lab to recognize and attack a protein called EGFR fou…

This study looked at how radiation therapy changes the brains and lives of children with central nervous system tumors. Researchers followed 76 kids for up to 5 years, using MRI scans, blood and urine tests, and surveys to measure memory, quality of life, and side effects. The go…

This study looked at whether it's possible to use a child's tumor DNA to choose their next treatment. 186 children with cancers that came back or didn't respond to standard therapy had their tumors analyzed. The goal was to see if this approach could be done quickly enough to gui…

This study gathered health and genetic information from 326 adults with rare central nervous system tumors. Participants completed surveys about their medical history, symptoms, and lifestyle, and provided a saliva sample for DNA analysis. The goal is to better understand what ca…